Inverse association between serum creatinine and mortality in acute kidney injury

Souza, Samilly Evangelista; Matos, Rodrigo Santos; Barros, Luísa Leite; Rocha, Paulo Novis

doi:10.5935/0101-2800.20140067

Cited by 12 publications

(8 citation statements)

References 26 publications

(31 reference statements)

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“…Previous studies have asserted a direct correlation between pre-admission creatinine level and mortality rate in patients undergoing CRRT (38,39). However, neither pre-dialysis nor post-dialysis serum creatinine levels were significantly associated with mortality rate in this study.…”

Section: Discussioncontrasting

confidence: 78%

Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients

Alirezaei¹,

Massoudi²,

Zare³

et al. 2019

J Nephropharmacol

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Section: Discussioncontrasting

confidence: 78%

Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients

Alirezaei¹,

Massoudi²,

Zare³

et al. 2019

J Nephropharmacol

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“…Factors known to be linearly associated with mortality, such as initial NIHSS score at admission, age, Cr, total cholesterol, and ESR, were used as continuous variables [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ].…”

Section: Methodsmentioning

confidence: 99%

Significantly Reduced Alanine Aminotransferase Level Increases All-Cause Mortality Rate in the Elderly after Ischemic Stroke

Yang

Jeon

et al. 2021

IJERPH

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(1) Background: A significantly reduced alanine aminotransferase (ALT) level is being recognized as a risk factor of increasing mortality in the elderly in relation to frailty. In the elderly, both frailty and ischemic stroke are not only common, but are also associated with mortality. The aim of this research was to investigate whether a significantly reduced ALT level increases the all-cause mortality rate in the elderly with ischemic stroke. (2) Methods: Between February 2014 and April 2019, a retrospective study of 901 patients with ischemic stroke admitted to a university-affiliated hospital was conducted. Cox proportional hazard regression was used to determine whether a significantly reduced ALT level is an independent risk factor for mortality in elderly patients after an ischemic stroke. (3) Results: This study enrolled 323 older adults (age ≥ 65 years) who were first diagnosed with ischemic stroke. The mean age of the participants was 76.5 ± 6.6 years, the mean survival time was 37.1 ± 20.4 months, and the number of deaths was 96 (29.7%). Our results showed that reduced ALT level (less than 10 U/L) increased the risk of all-cause mortality in the elderly after ischemic stroke (adjusted HR: 3.24, 95% CI: 1.95–5.41; p < 0.001). (4) Conclusions: A significantly reduced ALT level at the time of diagnosis (less than 10 U/L) is an independent risk factor that increases the mortality rate in the elderly after ischemic stroke.

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“…Estudo mostrou que de um total de 152 pacientes estratificados em dialíticos e não dialíticos, verificou-se que todos os dialíticos e 56,4% dos não dialíticos utilizaram ventilação mecânica invasiva e 52,6% dos dialíticos e 25,6% dos não dialíticos evoluíram com sepse (22) . Ao compararmos os dados deste estudo com outros encontrados (22)(23) , constatou-se similaridades com relação as características clínicas e, principalmente, nos desfechos. No entanto, neste estudo, esses fatores de risco, por mais que tenham sido evidentes em ambos os grupos, sempre se sobressaíram no grupo dialítico, com mortalidade mais elevada.…”

Section: Discussionunclassified

Recuperação De Pacientes Com Lesão Renal Aguda Dialítica E Não Dialítica

Cardoso¹,

Carneiro²,

Magro³

2017

Cogitare Enferm.

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RESUMO: O objetivo do estudo foi identificar a recuperação da função renal de pacientes com lesão renal aguda dialítica e não dialítica. Estudo observacional prospectivo e quantitativo, desenvolvido em unidade de terapia intensiva geral adulta de um hospital público do Distrito Federal, de janeiro a junho de 2015. Os dados foram coletados a partir de informações do prontuário eletrônico. Foram acompanhados 109 pacientes, desses 19 eram dialíticos, 10 (52,6%) do sexo feminino, com idade média de 54±19 anos. O grupo não dialítico constituiu-se por 90 pacientes predominantemente do sexo masculino 47 (52,2%), idade média de 55±21 anos. Entre os dois grupos, o dialítico apresentou como desfecho maior taxa de óbito (73,7%; p=0,009) e maior valor de Simplified Acute Physiology Score III (83,0 ± 10,2; p=0,0001). Apesar de o grupo dialítico acumular maior gravidade, o percentual de recuperação da função renal ocorreu em mais de 50% dos pacientes em ambos os grupos. DESCRITORES: Lesão renal aguda; Unidade de terapia intensiva; Recuperação de função fisiológica; Enfermagem. RECUPERAÇÃO DE PACIENTES COM LESÃO RENAL AGUDA DIALÍTICA E NÃO DIALÍTICA RECOVERY OF PATIENTS WITH ACUTE KIDNEY INJURY REQUIRING DIALYSIS OR NOTABSTRACT: The research objective was to identify the recovery of the kidney function in patients with acute kidney injury requiring dialysis or not. Prospective and quantitative observational study, developed at an adult general intensive care unit of a public hospital in the Federal District, Brazil, between January and June 2015. The data were collected based on information from the electronic patient history. One hundred and nine patients were monitored, 19 of whom required dialysis and 10 (52.6%) were female, with a mean age of 54±19 years. The group that did not require dialysis consisted of 90 patients, predominantly male with 47 (52.2%) and a mean age of 55±21 years. Among the two groups, the outcomes in the dialysis group were a higher death rate (73.7%; p=0.009) and higher Simplified Acute Physiology Score III (83.0±10.2; p=0.0001). Although the dialysis group accumulates more severe patients, the recovery percentage of the kidney function corresponded to more than 50% of the patients in both groups. DESCRIPTORS: Acute kidney injury; Intensive care units; Recovery of function; Nursing. El objetivo del estudio fue identificar la recuperación de la función renal de pacientes con lesión renal aguda dialítica y no dialítica. Estudio observacional prospectivo y cuantitativo, desarrollado en unidad de terapia intensiva general adulta de un hospital público del Distrito Federal, Brasil, de enero a junio del 2015. Los datos fueron recolectados a partir de informaciones del archivo electrónico. Fueron seguidos 109 pacientes, de los cuales 19 eran dialíticos, 10 (52,6%) del sexo femenino, con promedio de 54±19 años. El grupo no dialítico fue constituido por 90 pacientes predominantemente del sexo masculino 47 (52,2%), promedio de edad 55±21 años. Entre los dos grupos, el desfecho en el dialítico fue mayor tasa de...

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Inverse association between serum creatinine and mortality in acute kidney injury

Cited by 12 publications

References 26 publications

Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients

Continuous renal replacement therapy in Iran; current practice, indications and outcomes in hemodynamically unstable patients

Significantly Reduced Alanine Aminotransferase Level Increases All-Cause Mortality Rate in the Elderly after Ischemic Stroke

Recuperação De Pacientes Com Lesão Renal Aguda Dialítica E Não Dialítica

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