Skin lesions in chronic renal dialysis

Peres, Luís Alberto Batista; Passarini, Sandra Regina; Branco, Michele Ferreira de Barros Tocollini; Kruger, Luci Aparecida

doi:10.5935/0101-2800.20140008

Cited by 16 publications

(21 citation statements)

References 16 publications

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“…Dermatological lesions (physical skin signs) were present in 85% of cases; this result is similar to the results found in most series [9,[12][13][14]. Among these dermatological lesions, xerosis ( Figure 2) came first in our series as in others [6,9,12,15]. When it was ichthyosiform, it predominated in the legs and forearms.…”

Section: Discussionsupporting

confidence: 90%

Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin

Adégbidi

Akpadjan

Houngbo

et al. 2020

Dermatology Research and Practice

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Introduction. Dermatological damage in chronic hemodialysis patients is not uncommon. In Benin, to date, no study on the dermatological manifestations of chronic hemodialysis patients has been carried out. However, the presence of cutaneous signs is evident in these patients, and the need for dermatological care is not negligible. The objective of this study was to identify the epidemiological and clinical profile of the main dermatological manifestations presented by chronic hemodialysis patients at the NTH-HKM of Cotonou (Benin). Methods. This was a descriptive cross-sectional study conducted in chronic hemodialysis patients from May 15th to September 15th, 2018. Included were all patients seen during the study period who had been on hemodialysis for at least three months, had at least one dermatological manifestation, and gave verbal or written consent. Chronic hemodialysis patients who did not wish to participate in the survey were excluded. Results. 87 patients were included in the study for a hospital frequency of 33.8%. The sex ratio (male to female) was 2. The median age was 49 years (IQ [40.75–59]). Median age in hemodialysis was 36 months with two weekly sessions. The main dermatological manifestations were xerosis (48.3%), pruritus (34.5%), alopecia (14%), nail dystrophy (9.2%), equisegmented nails (8%), and melanoderma (8%). Pruritus was associated with a longer duration of hemodialysis sessions p=0.01, while xerosis, alopecia, and melanoderma were associated with seniority in hemodialysis. Conclusion. Cutaneous manifestations in hemodialysis patients were frequent and dominated by xerosis, pruritus, and alopecia. Factors associated with some of these dermatologic manifestations were seniority in hemodialysis, long duration of the hemodialysis session, and female gender.

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Section: Discussionsupporting

confidence: 90%

Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin

Adégbidi

Akpadjan

Houngbo

et al. 2020

Dermatology Research and Practice

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“…Peres et al30 reported that ecchymosis was present in 60% of their patients on HD. They observed that easy bruisability and increased skin fragility were worse in the patients who were on dialysis for a longer time.…”

Section: Discussionmentioning

confidence: 96%

Prospective study on prevalence of dermatological changes in patients under hemodialysis in hemodialysis units in Tanta University hospitals, Egypt

Mourad¹,

Hegab²,

Okasha³

et al. 2014

CCID

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IntroductionChronic hemodialysis patients experience frequent and varied mucocutaneous manifestations in addition to hair and nail disorders. The aim of this study was to evaluate the prevalence of dermatological changes among patients with end-stage renal disease under hemodialysis in a hemodialysis unit in Tanta University hospitals over a period of 6 months, and to evaluate the relations of these dermatological disorders with the duration of hemodialysis as well as with different laboratory parameters in these patients.Patients and methodsNinety-three patients with end-stage renal disease on regular hemodialysis (56 males and 37 females) were selected and included in this cross-sectional, descriptive, analytic study. Their ages ranged from 18–80 years. All patients underwent thorough general and dermatological examinations. Laboratory investigations (complete blood counts, renal and liver function tests, serum parathormone levels, serum electrolytes, alkaline phosphatase, random blood sugar, and Hepatitis C virus (HCV) antibodies) were evaluated.ResultsThis study revealed that most patients had nonspecific skin changes, including xerosis, pruritus, pallor, ecchymosis, hyperpigmentation, and follicular hyperkeratosis. Nail and hair changes were commonly found, especially half and half nail, koilonychia, subungal hyperkeratosis, melanonychia, onychomycosis, and brittle and lusterless hair. Mucous membrane changes detected were pallor, xerostomia, macroglossia, bleeding gums, aphthous stomatitis, and yellow sclera. There was a significant positive correlation between the presence of pruritus and serum parathormone level. There was a significant negative correlation between the presence of mucous membrane changes and hemoglobin level.ConclusionNonspecific mucocutaneous manifestations are common in patients on hemodialysis, particularly xerosis, dyspigmentation, and pruritus. Early and prompt recognition and treatment of dermatological conditions in patients on dialysis may improve their quality of life.

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“…Furthermore, the itching is associated to high rates of morbidity in clientele (3) . Affects 53.8% of patients on dialysis and your etiology is not completely understood, being difficult to treat, which raises the need for investigations that may suggest new relationships for your occurrence (4) . The rash is a symptom manifested in skin and/or mucous membranes, ranging from mild to intense, widespread and intermittent form.…”

Section: Introductionmentioning

confidence: 99%

“…The rash caused by CKD and dialysis does not present a known complement Physiology (2) , however stands out as a result of the accumulation of urêmicas substances, elevation of serum levels of calcium and phosphorus, secondary hyperparathyroidism, influences of substances that start itching, such as histamine and substance P, and the complement activation and interleukins by hemodialysis membranes (6) . Front of the main risk factors for the occurrence of the rash, the literature highlights the need to observe the serum levels of mineral metabolism, with the accompaniment of laboratory tests, mainly serum levels of calcium and phosphorus (4) . Ratifying the presented study identified the prevalence of pruritus in 53.8% of kidney patients undergoing dialysis.…”

Section: Introductionmentioning

confidence: 99%

Prurido no paciente em hemodiálise: associação com ingestão de fósforo e nível sérico de cálcio

Tinôco

Paiva

Macêdo

et al. 2018

Rev. Gaúcha Enferm.

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Resumo OBJETIVO Analisar a associação entre a ocorrência do prurido e a adesão à dieta prescrita, indicadores bioquímicos da função renal e a qualidade da hemodiálise, em pacientes renais crônicos. MÉTODO Estudo transversal, realizado em uma clínica de diálise no Nordeste do Brasil, com 200 pacientes submetidos à hemodiálise, no primeiro semestre de 2015. Para análise dos dados fez-se uso da estatística inferencial, através dos testes de Qui-Quadrado e Exato de Fisher; e teste de U de Mann Whitney. RESULTADOS O prurido esteve presente em 51% da amostra, associando-se estatisticamente com o consumo de fósforo (P=0,024) e a elevação do cálcio sérico (P=0,009). CONCLUSÃO O prurido em pacientes renais crônicos submetidos à hemodiálise sofre influência da não adesão adequada à dieta prescrita, além da elevação de indicadores bioquímicos da função renal.

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Skin lesions in chronic renal dialysis

Abstract: Our study showed the presence of more than one alteration per patient. Cutaneous alterations are frequent in patients on dialysis. Further studies are needed to better characterization and management of these dermatosis.

Cited by 16 publications

References 16 publications

Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin

Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin

Prospective study on prevalence of dermatological changes in patients under hemodialysis in hemodialysis units in Tanta University hospitals, Egypt

Prurido no paciente em hemodiálise: associação com ingestão de fósforo e nível sérico de cálcio

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