The effect of vitamin D deficiency on the retinal microvasculature: an observational case-control study

Karabulut, Müjdat; Karabulut, Sinem; Canbek, Tuğba Dübektaş; Sül, Sabahattin; Karalezlı, Aylin

doi:10.5935/0004-2749.20220089

Cited by 4 publications

(4 citation statements)

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“…Pandit et al [ 19 ] also claim that biodegradable materials will not only reduce waste but also increase wearing comfort and skin friendliness. Several authors report studies where biosourced and biodegradable filters have been made by electro‐spinning, e.g., based on gluten‐blended polyvinyl alcohol (PVA) [ 36 ] or carbon‐blended gluten nanofiber, [ 37 ] while other authors propose biopolymers like PVA and PLA [ 38 ] for electro‐spinning nanofilters. To the best of our knowledge, there are no biodegradable facemasks based on biosourced PEA.…”

Section: Discussionmentioning

confidence: 99%

Tunable and Biodegradable Poly(Ester Amide)s for Disposable Facemasks

Seoane,

Cattaneo,

Neuenschwander

et al. 2023

Macro Materials & Eng

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The widespread use of disposable facemasks during the COVID‐19 pandemic has led to environmental concern due to microplastic pollution. Biodegradable disposable facemasks are a first step to reducing the environmental impact of pandemics. Here, high‐performance facemask components based on novel poly(ester amide)s (PEA) grades synthesized from biosourced materials and processed into nonwoven facemask components are presented. PEA‐based polymers present an excellent compromise between mechanical performance and biodegradability. Importantly, the properties of the PEA can easily be tuned by changing the ratio of ester and amide, or by varying diol and diacid parts. Seven polymers are synthesized which are optimized for biodegradability and processability. Among them, two grades combines 1) electrospinning process compatibility with 2) full degradation within 35 days, using a normalized biodegradation test. The ultra‐thin filters thus developed are evaluated for performance on a custom‐made characterization bench. The filters achieve microparticle capture efficiency and air permeability comparable to commercial filters. Another PEA grade is optimized to reach optimal viscothermal properties that made it compatible with solvent‐free melt‐spinning process as demonstrated with continuous fiber production. Overall, this environmentally friendly solution paves the way for the fabrication of high‐performance fibers with excellent biodegradability for the next‐generation facemasks.

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Section: Discussionmentioning

confidence: 99%

Tunable and Biodegradable Poly(Ester Amide)s for Disposable Facemasks

Seoane,

Cattaneo,

Neuenschwander

et al. 2023

Macro Materials & Eng

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“…The full texts of remaining 12 papers underwent a meticulous review. Subsequently, one paper (19), identi ed as a case report, was excluded, while ve other papers were omitted due to lack of desired data for analysis (20)(21)(22)(23)(24). Finally, 5 case-control studies (25)(26)(27)(28)(29) and one prospective interventional study (30) were included in our meta-analysis.…”

Section: Study Characteristicsmentioning

confidence: 99%

Vitamin D Deficiency in Patients with Retinal Vein Occlusion: A Systematic Review and Meta-analysis

Daneshvar,

Akhlaghi,

Iranpour

et al. 2024

Preprint

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Background: This review aims to substantiate the correlation between vitamin D and retinal vein occlusion (RVO) within the medical literature. Method: A systematic review and meta-analysis were conducted in PubMed, SCOPUS, Web of Science, and Embase until December 10th , 2023. A meticulous literature search was undertaken to identify and analyze all observational-analytical papers reporting vitamin D levels in RVO patients. The principal outcome measures centered on the comparative assessment of vitamin D levels between patients with RVO (cases) and those devoid of RVO (controls). The protocol was registered in PROSPERO (code: CRD42024499853). Results: A total of six relevant studies consisting of 589 participants were included in this meta-analysis. The results indicated a significant association between vitamin D deficiency and increased risk of RVO (Odds ratio=14.51; 95% CI: [1.71, 122.59], P=0.014); and patients with RVO exhibited a significant decrease in serum vitamin D levels by 1.91ng/mL (95% CI: [-2.29, -1.54], P<0.001). Moreover, there was no significant difference observed in vitamin D levels between central RVO (CRVO) and branch RVO (BRVO) subtypes (P=0.63). Conclusion: RVO patients have more vitamin D deficiency than healthy controls. These results contribute to the growing body of evidence highlighting the intricate role of vitamin D supplementation as both a prophylactic and a treatment strategy in RVO. PROSPERO registration identifier: CRD42024499853

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“…[41] It is a prohormone that dissolves in fat and is initially synthesized in the skin upon exposure to sunlight. [4] Unfortunately, with the exception of egg yolks or fatty fish (such as sardines, herring, tuna, mackerel, salmon), the natural presence of vitamin D in food is minimal unless it is fortified, as seen in milk, dairy products, orange juice, or margarines. [36,37,38] Vitamin D is composed of a blend of vitamin D2 (ergocalciferol), derived from animal sources, and D3 (cholecalciferol), produced in plants and fungi.…”

Section: Introduction and Purposementioning

confidence: 99%

“…Following the second hydroxylation in the kidneys, calcidiol is converted into 1,25-dihydroxy vitamin D3 (1,25(OH)2D), alternatively referred to as calcitriol, overseeing the majority of biological functions. [4] Vitamin D is recognized for its role as a protective factor in various conditions, including cancer, cardiovascular and respiratory diseases, bone disorders, kidney issues, and other ailments. [5,19] Animal studies have demonstrated that vitamin D supplementation has the potential to diminish retinal inflammation.…”

Section: Introduction and Purposementioning

confidence: 99%

Association between deficient levels of vitamin D and the occurrence of selected retinal diseases

Żmijewska,

Maleszewska,

Sztybór

et al. 2024

J Educ Health Sport

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Introduction and Purpose: Vision originates in the eye's retina, a complex structure essential for processing visual information. The connection between nutritional inadequacy, particularly vitamin deficiencies, and overall health, including ocular health, has long been acknowledged. Recent studies highlight the potential impact of vitamin D, a crucial nutrient, on retinal health. The aim is to investigate the association between low levels of vitamin D and retinal diseases like age-related macular degeneration (AMD) and diabetic retinopathy (DR), and to evaluate the potential benefits of vitamin D supplementation or lifestyle changes for at-risk patients. Description of the State of Knowledge: AMD, a significant cause of blindness in the elderly, involves factors like oxidative stress and inflammation. Various stages of AMD require different treatments, with limited options for advanced stages. DR, a complication of diabetes, leads to conditions such as retinal ischemia and neovascularization. Both conditions are potentially influenced by vitamin D levels. Studies show mixed results regarding the impact of vitamin D on these diseases. Some suggest lower levels may increase risk, while others report no significant effect or even contradictory findings. Conclusions: While some studies indicate a potential association between low vitamin D levels and the occurrence of retinal diseases, discrepancies exist in the findings. Lower vitamin D concentrations may be linked to a higher frequency of AMD and DR, but the evidence is not consistent across all studies. Therefore, a more in-depth exploration of this subject is warranted to draw conclusive insights. It is crucial to consider supplementation or dietary changes in cases of vitamin D deficiency, given its potential impact on systemic health.

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The effect of vitamin D deficiency on the retinal microvasculature: an observational case-control study

Cited by 4 publications

References 0 publications

Tunable and Biodegradable Poly(Ester Amide)s for Disposable Facemasks

Tunable and Biodegradable Poly(Ester Amide)s for Disposable Facemasks

Vitamin D Deficiency in Patients with Retinal Vein Occlusion: A Systematic Review and Meta-analysis

Association between deficient levels of vitamin D and the occurrence of selected retinal diseases

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