Anterior segment optical coherence tomography in acute anterior uveitis

Abstract

Purpose: To analyze the corneal thickness and anterior chamber (AC) angle using anterior segment optical coherence tomography (AS-OCT) in patients with acute anterior uveitis (AAU). Methods: Twenty two patients (24 eyes) were included. All patients underwent complete ophthalmological examination, applanation tonometry and AS-OCT at diagnosis and fifteen days after treatment. Results: Average corneal thickness before treatment was 564.2 ± 44.2 µm, 580.0 ± 44.3 µm and 580.1 ± 2.9 µm, respectively in central, pericentral and paracentral cornea. Fifteen days after treatment a significant decrease of corneal thickness was observed, with 529.5 ± 33.1 µm (p=0.0091) and 542.6 ± 33.6 µm (p=0.0068), respectively in central and pericentral cornea; paracentral corneal thickness (557.8 ± 35.3 µm) thinning did not reach statistical significance (p=0.1253). There was no significant change in temporal AC angle between visits, 44.3 ± 14.4 degrees before treatment and 44.7 ± 14.7 degrees fifteen days after (p=0.9343), and mean intraocular pressure, 10.8 ± 4.5 mmHg before treatment and 12.3 ± 3.0 mmHg fifteen days after (p=0.1874). Conclusion: In the studied group, AS-OCT detected a decrease of corneal thickness after AAU treatment. Temporal AC angle and intraocular pressure did not change during the studied period. Keywords

Correlation between anterior chamber characteristics and laser flare photometry immediately after femtosecond laser treatment before phacoemulsification

“…The central and thinnest corneal thickness was significantly increased in the higher flare cohorts (100-249 +4249 photon counts/ms) 10 min post femtosecond laser treatment (Table 2); the increase of the corneal thickness was observed in studies of active AC inflammation due to the amount of inflammation and could be confirmed by our study results. 21,22 Similar findings were demonstrated in the flareo100 cohort compared to the flare cohort4249; AC depth, AC volume and AC angle were significantly deeper in the flareo100 cohort 10 min post femtosecond laser treatment (P = 0.001, P = 0.007, P = 0.003). Our findings regarding the AC depth, volume and angle were confirmed by Otsuki et al 23 Indeed, changes in AC depth are the most sensitive indicator of inflammatory activity in patients with anterior uveitis due to ciliary oedema.…”

Raised Intraocular Pressure in Nonjuvenile Idiopathic Arthritis-Uveitis Children: Risk Factors and Effect on Retinal Nerve Fiber Layer

“…Often we encounter very significantly raised IOPs and even with CCT adjustments, the children would still require treatment. 23,27 In conclusion, clinical awareness of the higher risk of raised IOP and glaucoma in younger children, those with chronic uveitis and higher peak IOP is important, as the consequent visual loss is irreversible. We speculated that monitoring of the peripapillary RNFL thickness in quiescent HU eyes in children may be useful in detecting RNFL thinning associated with glaucoma.…”

“…23,24 Often we encounter very significantly raised IOPs and even with adjustments with the central corneal thickness (CCT), the children would still require treatment.…”