Guidelines on the treatment of primary immune thrombocytopenia in children and adolescents: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Guidelines Project: Associação Médica Brasileira - 2012

Outcome of SARS-CoV-2 and immune thrombocytopenia in a pediatric patient

“…It is well established that newly diagnosed ITP in children is usually preceded by viral infections in the month prior to its onset. 7 …”

“…Considering that the natural evolution of ITP in children is remission in up to 12 months, the management of children with newly-diagnosed ITP consists of careful observation, regardless of the platelet count if there is only skin bleeding, or immunomodulatory treatment. First-line therapy for patients with newly-diagnosed ITP, platelets < 20,000/mm 3 and active bleeding includes IVIG, corticosteroids or anti-D. 7 …”

Genetic comparison of sickle cell anaemia cohorts from Brazil and the United States reveals high levels of divergence

“…Five RFLP-assessed haplotypes, named after the locations where they occur more frequently (Benin, Central Africa Republic or CAR, Cameroon, Senegal and Arab-Indian), are classically used to classify the HBB cluster. High fetal haemoglobin (HbF) levels are associated with the Senegal and Arab-Indian haplotypes, compared to the Benin, CAR and Cameroon haplotypes 3 . Individuals with CAR haplotypes tend to present the lowest HbF levels, while individuals with the Benin haplotype usually have intermediate HbF production levels 4 .…”

The care of a child with a newly diagnosed immune thrombocytopenia

“…Another recent guideline from Brasilia based some frequent questions on the treatment of ITP with recommendations as answers (7). Despite these guidelines that support an expectant noninterference approach for paediatric patients with ITP, many children still receive pharmacological treatment after diagnosis.…”