Brazilian Society of Pediatric Oncology - SOBOPE

Castro, Cláudio Galvão de; Macedo, Cristiane R

doi:10.5581/1516-8484.20110089

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…18,20 In 2013, the Paediatric Oncology in Developing Countries Committee of the SIOP (International Society of Paediatric Oncology) published a consensus guideline for the management of retinoblastoma in countries with limited resources 21 with clear ideas that can shape resource development. The Mexican National Strategy 22 and the Brazilian SOBOPE (Brazilian Society of Paediatric Oncology) 23 guidelines are also applicable at a national level with governmental support for treatment.…”

Section: Epidemiologymentioning

confidence: 99%

Retinoblastoma

Dimaras

Corson

Cobrinik

et al. 2015

Nat Rev Dis Primers

452

390

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Retinoblastoma is a rare cancer of the infant retina, which forms when both RB1 alleles mutate in a susceptible retinal cell, likely a cone photoreceptor precursor. Loss of the tumour suppressor functions of the retinoblastoma protein, pRB, leads to uncontrolled cell division and recurrent genomic changes during tumour progression. Although pRB is expressed in virtually all tissues, cone precursors have biochemical and molecular features that may sensitize to RB1 loss to enable tumourigenesis. Retinoblastoma is diagnosed in ~8,000 children each year worldwide. Patient survival is >95% in high-income countries, but <30% globally. However, outcomes are improving through increasing awareness for earlier diagnosis, new guidelines and sharing of expertise. Intra-arterial and intravitreal chemotherapy have emerged as promising methods to salvage eyes. Ongoing international collaborations will replace the multiple different classifications of eye involvement with standardized definitions to consistently assess eligibility, efficacy and safety of treatment options. Life-long follow-up is warranted since survivors of heritable retinoblastoma are at risk for developing second cancers. Defining the molecular consequences of RB1 loss in diverse tissues may open new avenues for treatment and prevention of retinoblastoma as well as second cancers in patients with germline RB1 mutations.

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Section: Epidemiologymentioning

confidence: 99%

Retinoblastoma

Dimaras

Corson

Cobrinik

et al. 2015

Nat Rev Dis Primers

452

390

View full text Add to dashboard Cite

show abstract

“…High‐quality pediatric oncology services and physician training programs have been available in large Brazilian cities for decades, Brazil offers public support for diagnosis and treatment to all children and adolescents with cancer. The national society SOBOPE, created in 1981, is the largest in the region 15 . There are at least 20 cancer registries in Brazil, and combined reports on incidence and survival of some tumors have been reported at a national level, but to date, there is no national cancer registry capable of reporting a national estimate of survival for children with cancer 16,17 …”

Section: Resultsmentioning

confidence: 99%

“…The national society SOBOPE, created in 1981, is the largest in the region. 15 There are at least 20 cancer registries in Brazil, and combined reports on incidence and survival of some tumors have been reported at a national level, but to date, there is no national cancer registry capable of reporting a national estimate of survival for children with cancer. 16,17…”

Section: Brazilmentioning

confidence: 99%

International Society of Paediatric Oncology (SIOP) Global Mapping Programme: Latin American Society of Pediatric Oncology (SLAOP) country‐level report

Cappellano,

Gorostegui,

Gonzalez‐Ramella

et al. 2024

Pediatric Blood & Cancer

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BackgroundLatin American countries are improving childhood cancer care, showing strong commitment to implement the Global Initiative for Childhood Cancer, but there are scant publications of the situation at a continental level.MethodsAs part of the International Society of Paediatric Oncology Global Mapping project, delegates of each country participating in the Latin American Society of Pediatric Oncology (SLAOP) and chairs of national pediatric oncology societies and cooperative groups were invited to provide information regarding availability of national pediatric cancer control programs (NPCCP), pediatric oncology laws, pediatric oncology tumor registries, and training programs and support to diagnosis and treatment.ResultsNineteen of the 20 countries participating in SLAOP responded. National delegates reported nine countries with NPCCP and four of them were launched in the past 5 years. National pediatric tumor registries are available in eight countries, and three provided published survival results. Fellowship programs for training pediatric oncologists are available in 12 countries. National delegates reported that eight countries provide support to most essential diagnosis and treatments and 11 provide partial or minimal support that is supplemented by civil society organizations. Seven countries have a pediatric oncology law. There are three international cooperative groups and four national societies for pediatric oncology.ConclusionDespite many challenges, there were dramatic advances in survivorship, access to treatment, and availability of NPCCP in Latin America. Countries with highest social development scores in general provide more complete support and are more likely to have NPCCP, training programs, and reported survival results.

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A framework to develop adapted treatment regimens to manage pediatric cancer in low‐ and middle‐income countries: The Pediatric Oncology in Developing Countries (PODC) Committee of the International Pediatric Oncology Society (SIOP)

Howard

Davidson

Luna‐Fineman

et al. 2017

Pediatric Blood & Cancer

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Many children with cancer in low-and middle-income countries are treated in hospitals lacking key infrastructure, including diagnostic capabilities, imaging modalities, treatment components, supportive care, and personnel. Childhood cancer treatment regimens adapted to local conditions provide an opportunity to cure as many children as possible with the available resources, while working to improve services and supportive care. This paper from the Adapted Treatment Regimens Working Group of the Pediatric Oncology in Developing Countries committee of the International Society of Pediatric Oncology outlines the design, development, implementation, and evaluation of adapted regimens and specifies levels of services needed to deliver them.

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Brazilian Society of Pediatric Oncology - SOBOPE

Cited by 4 publications

References 8 publications

Retinoblastoma

Retinoblastoma

International Society of Paediatric Oncology (SIOP) Global Mapping Programme: Latin American Society of Pediatric Oncology (SLAOP) country‐level report

A framework to develop adapted treatment regimens to manage pediatric cancer in low‐ and middle‐income countries: The Pediatric Oncology in Developing Countries (PODC) Committee of the International Pediatric Oncology Society (SIOP)

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