2013
DOI: 10.5216/cab.v14i3.13476
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Abstract: The aim of the present study was to report an outbreak of natural poisoning by Cestrum laevigatum in dairy cattle in the “Agreste” region of Pernambuco state, Brazil. Epidemiological and clinical data were collected. Among a lot of 60 cows, eight became ill and four died. Two cows underwent necropsy, during which fragments of the central nervous system, liver, gall bladder, spleen and kidney were collected for histopathlogical analysis. Blood samples were collected for hematological and biochemical tests. The … Show more

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Cited by 7 publications
(15 citation statements)
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“…In the experimental poisoning, necrotic lesions extended to the midzonal region and often converged with other centrilobular areas, forming bridges. Similar findings were observed in cattle and sheep experimentally poisoned with C. laevigatum (COUTINHO et al, 2013;LUGT et al, 1992;PEIXOTO et al, 2000) and in cases of natural poisoning in buffalo (BARBOSA et al, 2010). Centrilobular necrosis is common, because this portion of the lobe receives less oxygenated blood and is therefore susceptible to hypoxia, and has a greater mixed-function enzymatic activity capable of converting primary compounds into toxic substances (CULLEN;BROWN, 2013).…”
Section: Discussionsupporting
confidence: 71%
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“…In the experimental poisoning, necrotic lesions extended to the midzonal region and often converged with other centrilobular areas, forming bridges. Similar findings were observed in cattle and sheep experimentally poisoned with C. laevigatum (COUTINHO et al, 2013;LUGT et al, 1992;PEIXOTO et al, 2000) and in cases of natural poisoning in buffalo (BARBOSA et al, 2010). Centrilobular necrosis is common, because this portion of the lobe receives less oxygenated blood and is therefore susceptible to hypoxia, and has a greater mixed-function enzymatic activity capable of converting primary compounds into toxic substances (CULLEN;BROWN, 2013).…”
Section: Discussionsupporting
confidence: 71%
“…In the Northeastern region, there has only been one report of poisoning by this plant among the dairy cattle in the Agreste region of the State of Pernambuco (COUTINHO et al, 2013).…”
Section: Introductionmentioning
confidence: 99%
“…Sob condições naturais, a espécie mais frequentemente intoxicada é a bovina (Döbereiner et al 1969, Afonso & Santos 1995, Coutinho et al 2013, mas já foram relatados casos em bubalinos (Barbosa et al 2010), caprinos e ovinos (Tokarnia et al 2012). Apenas a intoxicação aguda foi observada nos casos espontâneos (Tokarnia et al 2012).…”
Section: Introductionunclassified
“…Coutinho et al (2013) descreveram um surto de intoxicação natural na região Agreste de Pernambuco afetando oito bovinos leiteiros, dos quais quatro vieram a morte, com evolução de 12 a 48 horas após o início da sintomatologia clínica. Os sinais clínicos observados na intoxicação aguda são apatia, anorexia, parada ruminal, dorso arqueado, constipação com fezes em formas de pequenas esferas, por vezes recobertas com muco e com estrias de sangue, tremores musculares, andar cambaleante e, às vezes, sialorreia (Tokarnia et al 2012).…”
Section: Introductionunclassified
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