Utilization of oxidation-reduction reaction of Folin-Ciocalteu’s phenol reagent in colorimetric determination of amlodipine in pharmaceutical dosage form
Abstract:A simple visible spectrophotometric method has been developed for determination of amlodipine in commercial tablets. Amlodipine (AMO) is 1,4-dihydropyridine derivative, this group when reacted with Folin-Ciocaluts phenol reagent in presence of 10% sodium carbonate, intense blue color was formed that exhibits maximum absorbance at wave length 745 nm. The intensity of color was found to be affected by many parameters. Optimization of the method parameters was done. The method was validated over a concentration r… Show more
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