Synthesis, characterization and antibacterial evaluation of novel 2-mercaptobenzothiazole derivatives bearing 2-aminonicotinonitrile moiety

Abstract

An efficient m derivatives (6 irradiation. Th of heterocycli Chalcones int the result con one. The syn Antibacterial types of bacte Cite this: Eur.

Modern Approaches to the Synthesis and Transformations of Practically Valuable Benzothiazole Derivatives

“…Conversion of the hydrazine moiety in 2-hydrazinobenzothiazole to the pyrazole ring and further functionalization of the latter was realized, as shown in Scheme 40 [ 66 ]. 2-Hydrazinobenzothiazole, prepared as in Scheme 39 , reacted with ethyl acetoacetate to give benzothiazolo-5-pyrazolone (A).…”

“…As 2-aminobenzothiazoles, 2-mercaptobenzothiazoles attract the interest of researchers due to their various biological activities viz. antimicrobial [ 18 , 19 , 66 , 67 , 68 , 69 ], anti-inflammatory and antioxidant [ 69 , 70 , 71 ], antitumor [ 72 , 73 , 74 ]. Agrochemicals with 2-mercaptobenzothiazole moiety in the molecule are used as fungicides of a wide spectrum [ 75 , 76 , 77 ], herbicides [ 78 ], insecticides [ 39 , 78 , 79 ].…”

Microwave assistant synthesis of trans-4-nitrostilbene derivatives in solvent free condition

“…Compared with conventional heating methods, higher yields, milder reaction conditions and shorter reaction times can be achieved [2,3]. Some reviews have been published on the application of microwaves in chemical synthesis [1,4,5].…”