2015
DOI: 10.5155/eurjchem.6.3.270-274.1242
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Abstract: A series of novel benzimidazole derivatives have been synthesized by the condensation of ophenylenediamine with 4-bromophenoxy acetic acid and product obtained was alkylated at the benzimidazole-NH with different electrophilic reagents. Subsequent reactions of the products by the Suzuki Coupling between benzimidazole derivatives and phenylboronic acid derivatives were accomplished. All these compounds were characterized by FT-IR, 1 H NMR, MS and elemental analysis. These compounds were screened for their poten… Show more

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Cited by 2 publications
(2 citation statements)
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“…The activity and structural diversity exhibited by compounds containing benzimidazole moiety has led to the discovery and development of novel and useful bioactive benzimidazole libraries from time to time. We have been interested in the synthesis of novel benzimidazole ring systems in connection with our ongoing project on benzimidazoles [16][17] . In continuation of our work on bioactive benzimidazole libraries, we herein describe our efforts towards the synthesis of a novel class of benzimidazole derivatives and their biological activity screening studies.…”
Section: Introductionmentioning
confidence: 99%
“…The activity and structural diversity exhibited by compounds containing benzimidazole moiety has led to the discovery and development of novel and useful bioactive benzimidazole libraries from time to time. We have been interested in the synthesis of novel benzimidazole ring systems in connection with our ongoing project on benzimidazoles [16][17] . In continuation of our work on bioactive benzimidazole libraries, we herein describe our efforts towards the synthesis of a novel class of benzimidazole derivatives and their biological activity screening studies.…”
Section: Introductionmentioning
confidence: 99%
“…Some of the important benzimidazole derivatives have been reported as thyroid receptor agonists [15], gonadotropin releasing hormone receptor antagonists [16], non-nucleoside HIV-1 reverse transcriptase inhibitors [17] and interestingly alkynyl benzimidazoles as modulators of metabotropic glutamate receptors [18] etc. We have also published some series of biologically active benzimidazoles [19][20][21]. Owing to the immense biological importance of benzimidazole derivatives, we now synthesized some novel class of benzimidazole derivatives and their biological activity screening studies.…”
Section: Introductionmentioning
confidence: 99%