A convenient synthesis and preparation of the derivatives of ethyl-6-(8-hydroxyquinolin-5-yl)-3-methylpyridazine-4-carboxylate as antimicrobial agents

One-pot synthesis of 5-[1-substituted 4-acetyl-5-methyl-1H-pyrrol-2-yl)]-8-hydroxyquinolines using DABCO as green catalyst

“…DABCO is an organic base that can act as nucleophile and is soluble in water. In continuation of our research program to develop environmentally friendly reactions [19][20][21][22], we report herein a simple, practical, and general three-component reaction for the construction of pyrrole derivatives by the reaction of 5-chloroacetyl-8-hydroxyquinoline, acetylacetone, and aryl-, heteroaryl-, and alkylamines in aqueous medium in the presence of DABCO.…”

A facile one-pot synthesis of novel 1-substituted 2-(8-hydroxyquinolin-5-yl)-1,5,6,7-tetrahydro-6,6-dimethyl- 4H-indol-4-one derivatives

“…[13][14][15][16][17] DABCO is an organic base that can act as a nucleophile. In view of this, and as part of our work on multi-component reactions, [18][19][20][21][22] we here report a simple, practical, and generally three-component reaction for the synthesis of novel indole derivatives by one-pot three-component reaction of 5-chloroacetyl-8-hydroxyquinoline, alkyl-, aryl-and heteroaryl-amines, and dimedone; the reaction is catalyzed by DABCO.…”