2014
DOI: 10.5155/eurjchem.5.2.374-379.1027
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Synthesis, characterization and in vitro biological evaluation of some new 1,3,5-triazine-bis-azomethine hybrid molecules as potential antitubercular agents

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Cited by 3 publications
(2 citation statements)
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“…Mycobacterium tuberculosis (TB) is a serious public health concern as it is a leading infectious cause of death. However, a number of new chemical compounds having significant antitubercular activity have been recently discovered, but no new drug has entered the market from the last 55 years [16]. The known drawbacks of current existing drugs with the emergence of MDR strains and the increasing occurrence of death due to TB have arisen interest in the discovery and development of new anti-tubercular drugs with novel mode of action.…”
mentioning
confidence: 99%
“…Mycobacterium tuberculosis (TB) is a serious public health concern as it is a leading infectious cause of death. However, a number of new chemical compounds having significant antitubercular activity have been recently discovered, but no new drug has entered the market from the last 55 years [16]. The known drawbacks of current existing drugs with the emergence of MDR strains and the increasing occurrence of death due to TB have arisen interest in the discovery and development of new anti-tubercular drugs with novel mode of action.…”
mentioning
confidence: 99%
“…Triazine known from a long period of time as a class of six membered heterocyclic compound containing nitrogen. In 1,3,5-triazine all the nitrogen atoms are present symmetrically therefore it is also called as symmetrical triazine or s-triazine [4]. Recently it has been discovered that 2,4,6-trisubstituted-1,3,5-triazine scaffolds act as a potent inhibitor of Mycobacterium tuberculosis (Mtb) H37RV.…”
mentioning
confidence: 99%