“…It is important that considerable activity was observed when the hydroxyl groups are substituted at different positions on the phenyl ring as seen in the case of compounds 4k, 5h, 4e and 5e-5g and the order of activity was 4k (2-OH,3-Br,5-Cl, MIC : 6.25 µg/mL), 5h (2,5-diOH, MIC : 6.25 µg/mL) > 4e (3-OC2H5,4-OH, MIC: 25 µg/mL), 5e (2-OH, MIC: 25 µg/mL), 5f (4-OH, MIC: 25 µg/mL), 5g (2,4-diOH, MIC: 25 µg/mL) respectively. The compounds 5i (MIC: 50 µg/mL) and 5j (MIC: 50 µg/mL) having the methyl group substitution on the phenyl ring at position 5 along with the hydroxyl group substitution at 6 (5j) and 2 (5i) positions, respectively showed poorer level of inhibitory activity when compared with that of the compounds (5e-h) possessing only hydroxyl group substitution [69][70][71][72].…”