A new series of 3N-substituted triazolo-[1,5-c]pyrimidine 7, 8 and 9 have been synthesized in good yields (78-91%) trough a facile method using substituted 2-amino-3-cyano-pyrans 1, 2-amino-3-cyano-4-methylfuran 2, 1-Phenyl-3-thiomethyl-5-aminopyrazole-4-carbonitrile 3 as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass, spectral data and DFT at B3LYP.
Graphic AbstractN N N N CN R N CN NH 2 OEt R CN H 2 N H N O CN RC(OEt) 3