European Journal of Chemistry volume 4, issue 2, P146-148 2013 DOI: 10.5155/eurjchem.4.2.146-148.756

Synthesis of new curcumin analogues from Claisen-Schmidt condensation

Nouara Ziani, Assia Sid, Albert Demonceau, Quentin Willem, Benjamin Dassonneville, Kaddour Lamara
Abstract: A series of new curcumin analogues were obtained by Claisen-Schmidt condensation of substituted benzaldehydes with cyclohexanone derivatives using the ratio of 1:2 of ketone to aldehyde in dilute ethanolic solution under base catalyzed (NaOH) conditions at room temperature in good yields. The structures of the synthesized compounds were confirmed by data of IR, 1 H NMR, and 13 C NMR spectra.
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