Efficient deprotection of Boc group in amines and sulfamides using Dawson heteropolyacid catalyst

A simple and eco-sustainable method for the sulfonylation of amines under microwave-assisted solvent-free conditions

“…22 Introduced by Gedye 23 and Giguere, 24 it has advantages like reduction of reaction times, enhancement of product yields, easy isolation of the nal product, ability to precisely control the temperature, etc. 25 In continuation of our interest towards development of useful green synthetic methodologies, [26][27][28][29][30] we report the successful use of microwave irradiation for the selective sulfonylation of various structurally amines. It is a facile and ecofriendly method for the preparation of sulfonamides wherein the use of solvents and catalysts is avoided.…”

Antibacterial, Cytotoxic and Genotoxic Assessment of New Sulfonamide Derivatives

“…Sulfonamides 1 – 5 were easily prepared in good yield (85–97 %), using chlorosulfonyl isocyanate (CSI) that is the suitable available reagent allowing the introduction of a sulfamide moiety. The reaction was carried out by three steps [35,36] …”

“…The reaction was carried out by three steps. [35,36] In the first step, to a solution of chlorosulfonyl isocyanate in anhydrous methylene chloride was added a solution of tertbutanol. The reaction takes place for 30 min.…”

A simple and highly efficient solvent- and catalyst-free synthesis of novelN-sulfamoyl imines

“…More recently, Zolfigol et al reported a green method for the synthesis of N-sulfonyl imines using WCl 6 as novel, highly facile and reusable catalyst (35). In continuation of our interest toward development of useful green synthetic methodology (36)(37)(38)(39)(40), we report the successful and efficient method for the synthesis of N-sulfonyl imines via the reaction of chloroethylsulfonamides with various aldehydes under solvent-and catalyst-free conditions.…”