Synthesis of novel 2-propenoyl amides, esters, heterocyclic compounds and their screening as antifungal and antibacterial agents

2‐Cyano‐N‐(thiophen‐2‐yl)acetamide in Heterocyclic Synthesis: Synthesis and Antibacterial Screening of Novel Pyrido[1,2‐a]thieno[3,2‐e]pyrimidine‐2‐carboxylate Moieties

“…Cyanoacetamide derivatives are interesting starting materials for the synthesis of a variety of bioactive molecules and agrochemicals . They are widely used as antimicrobial agents . In addition, they are versatile precursors for the synthesis of wide range of various nitrogen‐containing heterocycles .…”

Synthesis of Bioactive Heterocycles from 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile

“…31 Over the past decades, significant efforts have been devoted to develop the synthesis of pyrimidinethione derivatives, 32,33 as they are considered versatile synthons for the construction of many heterocycles of synthetic and biological importance. [34][35][36][37] Thus, in view of the above facts and in continuation of our efforts to construct heterocyclic compounds from pyran derivatives, and to study their biological potency, [38][39][40][41][42][43][44][45] it was of interest to synthesize a ring system combine both the pyrazole and the pyran moieties which might have good biological activity.…”

New Bis(dihydropyridine‐3,5‐dicarbonitrile) Derivatives: Green Synthesis and Cytotoxic Activity Evaluation

“…Substituted cyanoacetamides are important intermediates in the synthesis of a variety of agrochemicals, dyes, and pharmacologically active compounds . They were also found to exhibit significant biological activities as antifungal and antibacterial agents . In addition, they are versatile and convenient intermediates for the synthesis of wide variety of various nitrogen‐containing heterocyclic compounds .…”