A quick method for surveillance of 59 pesticide residues in fruits and vegetables using rapid three-dimensional gas chromatography (GC/MSD/µ-ECD/FPD) and LC/MS-MS

Tyagi, Yogesh Kumar; Gupta, Rajinder K.

doi:10.5155/eurjchem.2.4.524-534.438

Cited by 3 publications

(1 citation statement)

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“…Food samples were pretreated by a combination of acetonitrile LLE and dispersive solid‐phase extraction (dSPE) to remove impurities in the matrix. Over the past few years, QuEChERS has been used for preparation in the analysis of insecticides in fruits , vegetables , and other kinds of food products . Materials for QuEChERS extraction are often composed of primary‐secondary amines (PSA), anhydrous magnesium sulfate, and C 18 sorbents .…”

Section: Introductionmentioning

confidence: 99%

Determination of nicotine and its metabolites accumulated in fish tissue using hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Chang

Nguyen

Chang

et al. 2015

J of Separation Science

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The determination of nicotine and its major metabolites (cotinine and anabasine) in fish tissue was performed using liquid chromatography and tandem mass spectrometry. Marine and freshwater fish were purchased from local grocery stores and were prepared based on a quick, easy, cheap, effective, rugged, and safe sample preparation protocol. To determine the highly polar compounds, hydrophilic interaction liquid chromatography was also used. There were modest suppressions on measured nicotine signals (10%) due to the matrix effects from marine fish but no obvious effects on freshwater fish signals. Method validation was incorporated with internal standards and carried out with matrix-matched calibration. The detection limits for nicotine, cotinine, and anabasine were 9.4, 3.0, and 1.5 ng/g in fish, respectively. Precision was quite acceptable returning less than 8% RSD at low, medium, and high concentrations. Acceptable and reproducible extraction recoveries (70-120%) of all three compounds were achieved, except for anabasine at low concentration (61%). The method was then applied to define nicotine bioaccumulation in a fathead minnow model, which resulted in rapid uptake with steady state internal tissue levels, reached within 12 h. This developed method offers a fast, easy, and sensitive way to evaluate nicotine and its metabolite residues in fish tissues.

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Section: Introductionmentioning

confidence: 99%