2020
DOI: 10.5155/eurjchem.11.4.285-290.2023
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Abstract: Carbonohydrazide was used for synthetizing a new dissymmetrical bis-substituted Schiff base 1-(2'-hydroxybenzylidene)-5-(1'-pyridylethylidene)carbonohydrazone (2). A mono substituted compound (1-(pyridin-2-yl)ethylidene)carbonohydrazide (1) was firstly prepared by condensation reaction of carbonohydrazide and 2-acetylpyridine in 1:1 ratio. Secondly, compound 2 was obtained by condensation reaction of compound 1 and salicylaldehyde in 1:1 ratio. The prepared compounds were characterized by elemental analysis, i… Show more

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“…Cindric et al demonstrated that free benzohydrazone having cytotoxic activity against a THP-1 and HepG2 cell line saw its activity significantly increased after complexation with copper [23]. It is in this context that we have prepared transition metal and lanthanide complexes from ligands having hydrazine units [24][25][26][27][28][29]. In this work, we describe the synthesis and characterization of two complexes of cobalt(II) and copper (II) ions obtained from the N'-(1-(pyridin-2-yl)ethylidene)nicotinohydrazide (HL) ligand, which are characterized by elemental analysis, FT-IR, 1 H NMR, and 13 C NMR.…”
Section: Introductionmentioning
confidence: 97%
“…Cindric et al demonstrated that free benzohydrazone having cytotoxic activity against a THP-1 and HepG2 cell line saw its activity significantly increased after complexation with copper [23]. It is in this context that we have prepared transition metal and lanthanide complexes from ligands having hydrazine units [24][25][26][27][28][29]. In this work, we describe the synthesis and characterization of two complexes of cobalt(II) and copper (II) ions obtained from the N'-(1-(pyridin-2-yl)ethylidene)nicotinohydrazide (HL) ligand, which are characterized by elemental analysis, FT-IR, 1 H NMR, and 13 C NMR.…”
Section: Introductionmentioning
confidence: 97%