Determination of voglibose in pharmaceutical formulations by high performance liquid chromatography using refractive index detection

Lakshmi, K. S.; Rajesh, Tirumala

doi:10.5155/eurjchem.1.4.262-265.116

Cited by 11 publications

(4 citation statements)

References 8 publications

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“…The LOD and LOQ (limit of detection and quantification) were found to be 2.91 and 9.7 μg/mL. This method could be successfully used for the quantification of voglibose in pharmaceutical formulations [26].…”

Section: Introductionmentioning

confidence: 87%

Refractometric study on binary, ternary, and quaternary solutions made by water, methanol, ethanol, glycerol, D-glucose monohydrate (DGMH), sucrose, and sodium chloride at T = 293.15 K and atmospheric pressure

Koohyar

Nasiri²,

Kiani

2019

J. Mex. Chem. Soc.

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The glycerol, D-glucose monohydrate (DGMH), sucrose, and sodium chloride are used in food industries and the measurement of properties for these components and their aqueous solutions can be important. In this research work, the refractive indices for binary solutions of (methanol + glycerol), (ethanol + glycerol), ternary solutions of (water + glycerol + DGMH), (water + glycerol + sucrose), (water + sucrose + DGMH), (water + sucrose + ethanol), (water + ethanol + DGMH), (water + NaCl + DGMH), (water + methanol + NaCl), (water + ethanol + NaCl), (water + NaCl + glycerol), (water + sucrose + NaCl), and quaternary solutions of (water + ethanol + sucrose + DGMH), (water + ethanol + sucrose + glycerol), (water + NaCl + sucrose + glycerol) were measured in wide range of mole fractions at T = 293.15 K and atmospheric pressure. For binary solutions of this study, the changes of refractive index on mixing, ∆nD, were calculated in each mole fraction at T = 293.15 K. Also, the refractive index of binary solutions was fitted by a semi-empirical equation. The constant of this equation, Kr, was represented by Koohyar et al. in 2011. This constant can be used to investigate power of interactions between solute and solvent molecules. For ternary and quaternary solutions of this study, a semi-empirical equation was used to determine refractive indices at given temperature. The comparison between calculated and experimental refractive indices shows that there is a good agreement between them especially in lower molal concentrations.

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Section: Introductionmentioning

confidence: 87%

Refractometric study on binary, ternary, and quaternary solutions made by water, methanol, ethanol, glycerol, D-glucose monohydrate (DGMH), sucrose, and sodium chloride at T = 293.15 K and atmospheric pressure

Koohyar

Nasiri²,

Kiani

2019

J. Mex. Chem. Soc.

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“…Mallikarjuna Rao et al [1] presented RP-HPLC method development and validation for estimation of Voglibose in bulk and tablet dosage forms. Determination of voglibose in pharmaceutical formulations by high performance liquid chromatography using refractive index detection given by Karunanidhi Lakshmi et al [5]. Hong Zhang et al [2] reported 1 H and 13 C NMR analysis of Voglibose and its derivatives.…”

Section: Introductionmentioning

confidence: 99%

Structural and Vibrational Studies (FT-IR, FT-Raman) of Voglibose Using DFT Calculation

Solaichamy

Karpagam

2016

ILCPA

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In the present study, we report on the Molecular structure and infrared (IR) and FT-Raman studies of Voglibose (VGB) as well as by calculations based on the density functional theory (DFT) approach; utilizing B3LYP/6-31G(d,p) basis set. The targeted interpretation of the vibrational spectra intended to the basis of calculated potential energy distribution matrix (PED) utilizing VEDA4 program. Stability of the molecule arising from hyperconjugative interactions and charge delocalization was studied using natural bond orbital (NBO) analysis. The results show that change in electron density in the σ∗ and π∗ antibonding orbitals and E2 energies confirm the occurrence of intramolecular charge transfer within the molecule. The UV-Visible and NMR spectral analysis were reported by using TD-DFT and gauge GIAO approach respectively and their chemical shifts related to TMS were compared. The lowering of HOMO and LUMO energy gap appears to be the cause for its enhanced charge transfer interactions. Besides, molecular electrostatic potential (MEP) analysis was reported. Due to different potent biological properties, the molecular docking results are also reported.

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“…The potential applications of the refractive index of solvent mixture in the field of processes design, 14,15 design of biological environments, 16 analytical chemistry 17 and the search for greener liquid media, 18 are gaining theoretical and experimental interests. It has many applications in various industries like pharmaceutical, 19 petroleum, 20 and cosmetic. 21 In pharmaceutical and food industries, refractive index is often used to qualify control of crude intermediate and final products.…”

mentioning

confidence: 99%

Refractive Indices and Related Properties for Binary Mixtures of Methyl Acetate and Derivatives of Alkanolamines at Temperature Ranging from 293.15 to 313.15 K

Hyder¹,

Akhtar²

2021

ECS J. Solid State Sci. Technol.

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Refractive indices, n D, of two binary liquid systems of methyl acetate (MAc) + methylethanolamine (MEA), and MAc + dimethylethanolamine (DMEA) each at twenty-one different compositions at T = 293.15, 303.15 and 313.15 K under ambient pressure are reported. The effect of temperature on the n D values is relatively small and the higher the temperature, the lower the refractive index. From the n D data, deviation in refractive indices, Δn D, molar refraction, R m, as well as deviation in molar refractions, ΔR m are estimated. The Δn D and ΔR m were correlated with the Redlich–Kister equation. For each system, as a function of composition of alkanolamines, x 2, the Δn D form a single positive lobe with a maximum between 0.5 and 0.65 mole fraction of alkanolamine. The ΔR m for both the systems are positive, the maxima lying within x 2 = 0.3 to 0.5.

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Determination of voglibose in pharmaceutical formulations by high performance liquid chromatography using refractive index detection

Cited by 11 publications

References 8 publications

Refractometric study on binary, ternary, and quaternary solutions made by water, methanol, ethanol, glycerol, D-glucose monohydrate (DGMH), sucrose, and sodium chloride at T = 293.15 K and atmospheric pressure

Refractometric study on binary, ternary, and quaternary solutions made by water, methanol, ethanol, glycerol, D-glucose monohydrate (DGMH), sucrose, and sodium chloride at T = 293.15 K and atmospheric pressure

Structural and Vibrational Studies (FT-IR, FT-Raman) of Voglibose Using DFT Calculation

Refractive Indices and Related Properties for Binary Mixtures of Methyl Acetate and Derivatives of Alkanolamines at Temperature Ranging from 293.15 to 313.15 K

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