Descrição dos casos de síndrome congênita associada à infecção pelo ZIKV no estado de São Paulo, no período 2015 a 2017

Abstract

Objective: to characterize cases of congenital syndrome associated with Zika virus infection (CZS) and other infectious etiologies, resident in the state of São Paulo, Brazil, from October 30, 2015, to June 30, 2017. Methods: this was a descriptive study of suspected cases of CZS and other infectious etiologies notified on the Public Health Events Registry. Results: 960 cases were investigated up to epidemiological week 26/2017, and 146 were confirmed for congenital infection; of these, 59 (40.4%) were confirmed for congenital infection without etiological identification and 87 (59.6%) with laboratory confirmation, of which 55 were congenital syndrome associated with Zika virus and 32 were congenital syndrome associated with other infectious agents. Conclusion: this study enabled the detection of 23.9% CZS cases among suspected cases of infectious etiology.

Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018

“…Similarly, in other studies [17–18], most CZS cases were diagnosed in 2016; however, new cases are still reported despite the end of the ZIKV fever epidemic [3]. The existence of one confirmed CZS case in 2017 and two more occurrences of potential CZS in 2018 shows that its cumulative prevalence has increased even with a decreased incidence of ZIKV fever in pregnant women and the general population (S1 and S2 Tables).…”

“…Regarding STORCH related cases among the total reports, data showed that cytomegalovirus Toxoplasma gondii and Treponema pallidum were identified as teratogenic etiologic agents for some cases. These agents were already present in other studies classifying RESP data [16–18]. Similarly to the CZS, these infectious etiologies also produce congenital syndromes leading to microcephaly [9,23,24].…”

“…In contrast to other studies that quantified CZS in other regions [16–18], we employed primary data obtained from both an active search and by performing clinical assessments of infants; in addition to screening secondary data from RESP, SINASC and SINAN. Through this method, we determined the clinical status of infants with CZS after almost two years following the ZIKA epidemics in Mato Grosso do Sul.…”

Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: A living systematic review

“…Traveller/non-traveller populations: In this update, we found further evidence that congenital abnormalities occurred in infants born to women travellers returning from ZIKV-affected areas and women remaining in those areas. In total, 25 publications report on 272 congenital abnormalities due to ZIKV infection in travellers 27, 29, 30, 32, 34, 36, 38, 42, 45, 56, 58, 61, 89, 94, 98, 109, 117, 122, 123, 137, 140, 151, 153, 166, 173 , with 109 publications reporting congenital abnormalities due to ZIKV in 2652 non travellers 24– 26, 28, 31, 33, 35, 37, 39– 41, 43, 44, 46– 48, 50, 51, 54, 57, 60, 62– 79, 81, 83– 85, 87, 88, 90– 93, 95– 97, 100, 101, 104– 106, 110– 113, 115, 116, 118, 119, 121, 124– 135, 142– 147, 149, 152, 154, 156– 164, 167, 168, 171, 172, 175– 180, 182, …”

A Importância Da Fisioterapia Em Paciente Com Microcefalia Congênita Por Zika Vírus: Relato De Caso

“…Foi observado que 12 mulheres, entre as que tinham o tônus flácido, tiveram reduções entre 0,4 -0,6 cm, 1 puérpera entre 0,7 -0,9 cm e também 1 mulher entre 1,0 -1,2 cm. Das que possuíam tônus abdominal normal, 4 puérperas reduziram entre 0,4 -0,6 cm, 9 entre 0,7 -0,9 cm e 3 mulheres reduziram entre 1,0 FORNARI, 2016;MARTINS et al, 2018;DUFFY et al, 2009;BOS et al, 2018) Em 2014 foram notificados os primeiros casos, com foco na região Nordeste (MOLINA, et al, 2007).…”