Prevalência e carga parasitária da esquistossomose mansônica antes e depois do tratamento coletivo em Jaboatão dos Guararapes, Pernambuco

Abstract

the collective treatment contributed to reducing the rate of positivity in endemic areas.

Situação epidemiológica e controle da esquistossomose em Pernambuco: estudo descritivo, 2010-2016*

“…This result may possibly be related to shortage of health professionals, absence of positive case referral to health centers, as well as weaknesses in mobilizing the population to get treated with praziquantel. [22][23][24] Reduction in schistosomiasis positivity and parasite load and reduction in positivity for other helminthiases did not occur in a uniform manner between the Health Regions: those belonging to the Zona da Mata region had the worst results. Overall reduction may be associated with mass treatment being implemented in hyperendemic places.…”

“…7 Mass treatment takes place by administrating broad-spectrum drugs (praziquantel, albendazole, mebendazole), which given their simplicity -increase their scope when they are combined, in addition to reducing health system costs . 7,9,24,26,27 A study of schistosomiasis hyperendemic sites in Jaboatão dos Guararapes between 2011 and 2013, confirmed that mass treatment was useful for reducing both positivity and parasite load. 24 Individuals with positive test results for schistosomiasis and other helminthiases continuing to be found in traditionally endemic regions is related both to issues concerning the physiopathology of severe forms of the disease, in places where socio-economic conditions are precarious, and also to the inefficacy of praziquantel as an isolated strategy for eliminating schistosomiasis in hyperendemic regions.…”

“…7,9,24,26,27 A study of schistosomiasis hyperendemic sites in Jaboatão dos Guararapes between 2011 and 2013, confirmed that mass treatment was useful for reducing both positivity and parasite load. 24 Individuals with positive test results for schistosomiasis and other helminthiases continuing to be found in traditionally endemic regions is related both to issues concerning the physiopathology of severe forms of the disease, in places where socio-economic conditions are precarious, and also to the inefficacy of praziquantel as an isolated strategy for eliminating schistosomiasis in hyperendemic regions. A study of the use/efficacy of this medication on its own when administered for four years (2010-2014) in 67 Kenyan children found that the parasite load in 15 of them did not reduce, highlighting the parasite's ability to persist in endemic areas despite systematic treatment.…”

“…Overall reduction may be associated with mass treatment being implemented in hyperendemic places. 7,24,25 This strategy was proposed in order to control/eliminate neglected tropical diseases in places with positivity equal to or greater than 10%, considering the large number of false-negative results found in parasitology tests. 7 Mass treatment takes place by administrating broad-spectrum drugs (praziquantel, albendazole, mebendazole), which given their simplicity -increase their scope when they are combined, in addition to reducing health system costs .…”

“…29 Socio-economically precarious communities where low schooling levels together with environmental problems prevail, are characterized by these additional factors which result in these problems continuing, within a context in which reinfection is facilitated. [1][2][3][4][5][6][7]9,10,12,14,16,18,[23][24][25][26][27][28][29] The reduction in the percentage of positivity for other helminthiases may be associated with treatment with low toxicity medication (albendazole, mebendazole), which has taken place for decades in Brazil and has been reinforced by SANAR. 7,25 Data from the national survey on the prevalence of Manson's schistosomiasis and geo-helminthiases showed that periodic use of these low cost and easy to administer forms of medication is responsible for the reduction in approximately 80% of cases of other helminthiases.…”