Vocabulary plays a key role in speech production, affecting multiple stages of language processing. This pilot study investigates the relationships between second language (L2) learners’ lexical access and their speaking fluency, speaking accuracy, and speaking complexity. Fifteen L2 learners of Chinese participated in the experiment. A task-specific, native-referenced vocabulary test was used to measure learners’ vocabulary size and lexical retrieval speed. Learners’ speaking performance was measured by thirteen variables. The results showed that lexical access was significantly correlated with learners’ speech rate, lexical accuracy, syntactic accuracy, and lexical complexity. Vocabulary size and lexical retrieval speed were significant predictors of speech rate. However, vocabulary size and lexical retrieval speed each affected learners’ speaking performance differently. Learners’ speaking fluency, accuracy, and complexity were all affected by vocabulary size. No significant correlation was found between lexical retrieval speed and syntactic complexity. Findings in this study support the Model of Bilingual Speech Production, revealing the significant role lexical access plays in L2 speech production.