ALK+ Anaplastic large cell lymphoma with extensive cardiac involvement: A rare case report and review of the literature

Nambiyar, Kaniyappan; Gupta, Kirti; Debi, Uma; Sinha, Saroj Kant; Kochhar, Rakesh

doi:10.4322/acr.2020.231

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2024

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“…1 Anaplastic large-cell lymphoma (ALCL) accounts for 3% of adult cases of non-Hodgkin’s lymphoma, and only case reports of cardiac involvement have been described. 2 , 3 , 4 , 5 This poorly differentiated lymphoma is classically diagnosed by CD30 positive staining and lack of B-cell (CD20) and T-cell markers (CD3, CD4, CD8). 2 Prognosis of primary cardiac lymphoma is generally poor due to delayed diagnosis and aggressive disease course.…”

Section: Introductionmentioning

confidence: 99%

A Right Atrial Mass with Fever and Cutaneous Nodules

Gao

Koh

Alam

et al. 2022

Methodist DeBakey Cardiovascular Journal

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Primary cardiac tumors, although exceedingly rare, should be considered in the differential diagnosis during workup of any cardiac mass. Extranodal cardiac lymphomas have a natural aggressive course due to delayed diagnosis. We present a 71-year-old male with a dual-chamber pacemaker who presented with fevers and new cutaneous nodules. He was found to have a right atrial primary anaplastic large-cell lymphoma and had a complete metabolic response after chemotherapy. Our case highlights the importance of a multimodality approach in the diagnosis of cardiac tumors and during follow-up after treatment.

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