2017
DOI: 10.4025/jphyseduc.v28i1.2860
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Abstract: RESUMOA relação entre a acidose metabólica e o desempenho esportivo tem sido investigada ao longo dos anos através de manipulações do pH sanguíneo e muscular. Entre as formas de manipulação do pH, o cloreto de amônio (NH 4 Cl) é o componente químico mais utilizado quando se pretende induzir um estado de acidose sanguínea previamente ao exercício. Entretanto, investigações acerca da ação desse agente sobre o desempenho esportivo ainda podem ser consideradas escassas, quando foram realizados apenas dois estudos … Show more

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Cited by 3 publications
(2 citation statements)
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“…3). Blood lactate concentrations are also decreased in acidosis, likely due to the attenuation of glycolytic activity [23]. This may negatively impact training adaptations as lactate signaling can influence mitochondrial biogenesis [24] and the chronic adaptive response to training [25].…”
Section: Buffering Agentsmentioning
confidence: 99%
“…3). Blood lactate concentrations are also decreased in acidosis, likely due to the attenuation of glycolytic activity [23]. This may negatively impact training adaptations as lactate signaling can influence mitochondrial biogenesis [24] and the chronic adaptive response to training [25].…”
Section: Buffering Agentsmentioning
confidence: 99%
“…[NH 3 ] on the other hand being a weak base with a dissociation constant (kb) of 1.80 × 10 −5 will only partially ionize to produce ammonium cations and hydroxide anions. Therefore, a decrease in pH and the HCO 3 - concentrations is expected after the NH 4 Cl administration [ 22 ]. The blood pressure measurements of the conscious rats by a tail-cuff showed an increase in the mean arterial pressure starting at week 5, and it was sustained through week 8 in the acidotic rats as compared to that of the control group.…”
Section: Discussionmentioning
confidence: 99%