Abstract:Ischemic heart disease is the leading cause of death and loss of cardiovascular health worldwide. 1 In Brazil, although age-standardized cardiovascular mortality rate has declined in recent decades, coronary heart disease also remains the leading cause of death. [2][3] The increasing prevalence of cardiovascular risk factors, due to growing urbanization, is involved in this scenario. 4 The twentieth century has witnessed a remarkable evolution in the understanding of pathogenesis, treatment, and clinical cons… Show more
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