“…One theoretical benefit of coronary artery bypass graft over PCI relies on the idea that the graft bypasses long segments of proximal coronary plaques, and the patient would be protected from MI if any of those ruptures, whereas the stents protect only the stented segment. 14 In conclusion, Kalkan et al 8 demonstrated that patients with higher CHA 2 DS 2 VASc score have higher rSS, which means higher CAD severity. Based on recent evidence, those patients might consequently be at higher risk of plaque rupture and cardiovascular events, such as MI or death, and therefore would benefit from more aggressive plaque stabilizing therapies.…”