Pneumomediastinum in a patient with COVID-19

COVID-19 and spontaneous pneumomediastinum: a rare complication

“…Thus, only a few COVID-19-related pneumomediastinum cases with fatal outcomes have been reported 1 . An emerging pressure gradient between the alveoli and surrounding structures may cause alveolar rupture, with air leaking into the interstitium, following the bronchovascular bundle toward the hilum and spreading through the mediastinum 2 , 3 . Although this is a rare manifestation of COVID-19, physicians in pandemic settings should be aware of this complication.…”