Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults

Barban, Juliana Bernardo; Simões, Belinda Pinto; Moraes, Bruna Del Guerra de Carvalho; Anunciação, Cássia Rehem da; Rocha, Cristiane Santos da; Pintor, Daniela Cristina Querino; Guerra, Daiane Cristina; Silva, Deise Andrade; Brandão, Edith de Castro Martins; Kerbauy, Fábio R.; Pires, Fernanda Ramos de Oliveira; Morais, Graciele Lima; Filho, Jayr Schmidt; Sicchieri, Juliana Maria Faccioli; Barroso, Karine Sampaio Nunes; Viana, Luciana Verçoza; Rocha, Maria Cristina Pauli da; Guimarães, Maysa Penteado; Lazzari, Natalia Leonetti Couto; Hamerschlak, Nelson; Ramos, Plinio Patricia; Gomes, Plinio Nascimento; Mendonça, Priscila da Silva; Oliveira, Raquel Candido de; Scomparim, Renata Corrêa; Chiattone, Ricardo; Diez‐Garcia, Rosa Wanda; Cardenas, Thais de Campos; Miola, Thais Manfrinato; Costa, Thalita Cristina de Mello; Rocha, Vanderson; Pereira, Andréa Z

doi:10.31744/einstein_journal/2020ae4530

Cited by 7 publications

(47 citation statements)

References 248 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The immediate and serial nutritional status assessment of all pre-HSCT patients is required due to expected nutritional issues associated with the conditioning regimen[ 42 ]. In addition, nutritional status assessment with a validated tool is necessary during and after HSCT[ 43 ].…”

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

“…This assessment should be made according to the protocol of each institution at all stages of HSCT. It is recommended that the nutritional status of patients is evaluated during phases of admission, the onset of a conditioning regimen, the day of stem cell infusion, the onset of immunosuppression, hospital discharge, 1–3 mo after HSCT, 6 mo after HSCT and 1 year after HSCT[ 43 ].…”

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

“…In outpatients, nutritional assessment should be performed within the first 15 d in patients with nutritional risk and within 30 d in those with no risk. Also, inpatients should be assessed up to 48 h after hospitalization and re-evaluated after 7 d. Weekly re-evaluation should be done until the patient is discharged[ 33 , 43 ].…”

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

“…Although ESPEN and ASPEN recommend routine malnutrition screening for HSCT patients, there is no consensus on how to evaluate malnutrition in these patients[ 45 ]. The nutritional status of these patients can be evaluated using a validated screening tool, such as NRS-2002, MUST, the Malnutrition Screening Tool or the MNA-Short Form (MNA-SF)[ 43 ]. NRS-2002 is advised due to its easy applicability by ESPEN[ 48 ].…”

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

See 3 more Smart Citations

Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update

Akbulut

Yeşildemir

2021

WJSC

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) is caused by the newly discovered SARS-CoV-2. Hematopoietic stem cell transplantation (HSCT) is a high-risk procedure. The novelty of COVID-19 has created more uncertainty during all phases of HSCT. It is thought that HSCT patients taking immunosuppressive agents are more likely to contract COVID-19 than healthy individuals are. Appropriate care precautions should be taken with patients undergoing HSCT to minimize the risk of COVID-19, and appropriate treatment methods must be followed in patients infected with COVID-19. Malnutrition has become a significant problem in HSCT patients during the COVID-19 pandemic. The causes of malnutrition in HSCT patients are multifactorial. However, the most important reason is the decrease in energy and nutrient intake. The HSCT procedure can lead to many complications such as dysgeusia, mucositis, diarrhea, constipation, xerostomia and vomiting/nausea. Improving the nutritional status of HSCT patients by managing each of these special complications with an appropriate nutritional approach is essential for successful engraftment. This review aims to provide a comprehensive overview of the specific complications affecting the nutritional status of HSCT patients and their nutritional approach during the challenging COVID-19 pandemic.

show abstract

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

Section: Assessment Of Nutritional Status In Hsctmentioning

confidence: 99%

See 2 more Smart Citations

Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update

Akbulut

Yeşildemir

2021

WJSC

View full text Add to dashboard Cite

show abstract

“…Stem cell transplantation technology was established in the 1950s (9). Each year, numerous stem cell transplantation cases were reported globally (10). It has been demonstrated that stem cell transplantation is an effective strategy in treating a variety of diseases including severe and refractory autoimmune diseases (AD) (11), non-rhabdomyosarcoma soft tissue sarcomas (12), kidney diseases (13), and multiple sclerosis and immune-mediated neurological diseases (14).…”

Section: Introductionmentioning

confidence: 99%

Umbilical Cord Blood-Derived Mesenchymal Stem Cells Transplantation Decreases Incidence of Liver Cancer in End-Stage Liver Disease Patients: A Retrospective Analysis Over 5 Years

Luo

Lai

Tian

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: End-stage liver disease (ESLD) is the final stage of a liver disease, which is characterized by liver cirrhosis. ESLD largely increases possibility of liver cancers in the world. The stem cell transplantation has become an emerging therapy to treat various liver diseases including ESLD, while whether it causes liver cancer remains unclear. The study aims to analysis the long-term therapeutic effect of umbilical cord blood-derived mesenchymal stem cells (UC-MSCs) transplantation in ESLD patients. Patients and Methods: 50 ELSD patients of non-UC-MSCs transplantation and 45 ELSD patients of UC-MSCs transplantation were retrospectively analyzed. The clinical outcomes in clinical and biochemical data, complications, and quality of life were recorded at 3, 6, 12, 36, and 60 months. Results: It was found that the incidence of liver cancer was much lower in ESLD patients with UC-MSCs transplantation than in ESLD patients without UC-MSCs transplantation (12% VS 2.2%). The survival percentage was improved by treatment with UC-MSCs transplantation compared with non-UC-MSCs transplantation in ESLD patients during the five years follow-up. The inflammation and fibrosis scores were decreased in the ESLD patients with UC-MSCs transplantation. The liver cirrhosis was largely improved, and Child-Pugh scores were decreased. Conclusions: UC-MSCs transplantation is able to decrease the risks of liver cancers in ELSD patients. The reduction of liver cancer incidence might be related to decrease of inflammation by UC-MSCs transplantation. More efforts should be investigated towards increasing the number of patients and follow-up time to further verify the therapeutic benefits of UC-MSCs translations in treating liver cancers.

show abstract

Vitamin requirements during stem cell transplantation: a systematic review

Segon

Lam

Chan

et al. 2022

Support Care Cancer

View full text Add to dashboard Cite

Patients undergoing stem cell transplantation (SCT) are at high risk of malnutrition during the acute post-transplantation period. This systematic review aimed to collate and analyse the evidence for vitamin requirements post-SCT. A systematic search of five databases was conducted to include studies published until March 2021. The review utilised the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) framework. Inclusion criteria consisted of adults undergoing SCT who received vitamin supplementation or had their vitamin levels monitored up to 100 days post-SCT. Studies with paediatric patients or those that looked at vitamin derivates such as folinic acid were excluded. Main outcomes included vitamin deficiency and relevant clinical outcomes. Eleven studies (n = 11) were eligible for inclusion with five rated as neutral quality and six as positive quality. Five studies focused on allogenic SCT, two on autologous SCT and the remaining included a mix of both. Eight studies monitored vitamins levels post-SCT, and seven studies provided vitamin supplementation. Three studies (one provided supplementation) found a high prevalence of vitamin D deficiency (23–60%) prior to SCT. Findings indicate an unclear association between vitamin deficiency and post-SCT complications including acute graft-versus-host-disease, oral mucositis, and mortality. The GRADE certainty of evidence across these outcomes was low or very low. It is unclear if supplementation is needed during SCT, though assessing vitamin D levels prior to transplant should be considered. Further large observational studies or randomised control trials are required to establish vitamin requirements and guide supplementation protocols during SCT.

show abstract

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults

Cited by 7 publications

References 248 publications

Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update

Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update

Umbilical Cord Blood-Derived Mesenchymal Stem Cells Transplantation Decreases Incidence of Liver Cancer in End-Stage Liver Disease Patients: A Retrospective Analysis Over 5 Years

Vitamin requirements during stem cell transplantation: a systematic review

Contact Info

Product

Resources

About