2012
DOI: 10.2478/s11535-012-0036-1
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Abstract: AbstractSecondary metabolites obtained from Actinomycetales provide a potential source of many novel compounds with antibacterial, antitumour, antifungal, antiviral, antiparasitic and other properties. The majority of these compounds are widely used as medicines for combating multidrug-resistant Gram-positive and Gram-negative bacterial strains. Members of the genus Streptomyces are profile producers of previously-known secondary metabolites. Actinomycetes have been isolated fr… Show more

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Cited by 104 publications
(86 citation statements)
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“…The antimicrobial activities of microorganisms from Antarctica, especially bacteria, have only been investigated recently. Antibiotic activities of culturable Antarctic bacteria have been reported for Actinobacteria, Gammaproteobacteria, bacilli and cyanobacteria (Moncheva et al 2002;Nedialkova & Naidenova 2004;O'Brien et al 2004;De Souza et al 2006;Lo Giudice et al 2007b;Biondi et al 2008;Shekh et al 2011;Solecka et al 2012;Dong et al 2013;Encheva et al 2013;Asencio et al 2014). It is known that culture conditions have a major impact on the production of microbial bioactive secondary metabolites such as antibiotics.…”
Section: Antimicrobial Activitymentioning
confidence: 99%
“…The antimicrobial activities of microorganisms from Antarctica, especially bacteria, have only been investigated recently. Antibiotic activities of culturable Antarctic bacteria have been reported for Actinobacteria, Gammaproteobacteria, bacilli and cyanobacteria (Moncheva et al 2002;Nedialkova & Naidenova 2004;O'Brien et al 2004;De Souza et al 2006;Lo Giudice et al 2007b;Biondi et al 2008;Shekh et al 2011;Solecka et al 2012;Dong et al 2013;Encheva et al 2013;Asencio et al 2014). It is known that culture conditions have a major impact on the production of microbial bioactive secondary metabolites such as antibiotics.…”
Section: Antimicrobial Activitymentioning
confidence: 99%
“…However, in view of phylogenetic studies, actinomycetes have been classified as distinct from fungi and gram-positive or gram-negative bacteria (Embley and Stackebrandt, 1994). Actinomycetes are ecosystem decomposers that are widely distributed in the soil, and they are well known to produce secondary metabolites (Solecka et al, 2012;Newman and Hill, 2006;Bérdy, 2005;Bull et al, 2000), notably antibiotics (Strohl, 2004), antitumor agents (Olano et al, 2009), immunosuppressive agents (Al-Garni et al, 2014;Bamzadeh et al, 2014;Mann, 2001), antidiabetic agents (Kulkarni-Almeida et al, 2011) and…”
Section: Introductionmentioning
confidence: 99%
“…Actinobacteria are a predominant source of antibiotics [1,2] with Streptomyces as the major source of bioactive compounds [3]. Actinobacteria are found in soils although their isolation has focused on other unexplored habitats [2].…”
Section: Introductionmentioning
confidence: 99%