Health-related quality of life of pediatric intensive care survivors

Abstract

Objective: To assess the health-related quality of life (HRQoL) of children surviving to pediatric intensive care discharge. Methods:A prospective evaluation of HRQoL at admission and 6 months later was carried out with children aged 6 years or more, admitted to three tertiary pediatric intensive care units (PICUs) from May 2002 to June 2004. HRQoL was measured with the Health Utilities Index Mark 3 (HUI3) questionnaire, administered to a child's proxy. Results:From the 517 eligible admissions, 44 children died in the PICU (8.5%) and 320 cases were evaluated at admission; among those, follow-up data were available in 252 cases. There were no statistically significant differences between preadmission and follow-up HUI3 global scores (medians [interquartile range] of 0.86 [0.42-1.00] and 0.83 [0.45-1.00]; p = 0.674, respectively). At the individual level, 21% of children had their HRQoL unchanged, improvement was seen in 40% and deterioration in 38% of the cases. Severe disability before admission (HUI3 global score < 0.70) was present in 36% of the cases, with improvement at the 6-month follow-up in 60% of them. Among those with deterioration of HRQoL at follow-up, 45% were trauma victims. Conclusions:Although the HRQoL was globally similar in both evaluations, several differences were found at the individual level. Children with low preadmission HRQoL (severe disability) may benefit from pediatric intensive care, since many of these children improved their HRQoL compared to preadmission status. ResumoObjetivo: Avaliar a qualidade de vida relacionada à saúde (QVRS) de crianças sobreviventes à alta da terapia intensiva pediátrica. Métodos:Foi realizada uma avaliação prospectiva da QVRS na admissão e após 6 meses em crianças com idade igual ou superior a 6 anos, internadas em três unidades de terapia intensiva pediátricas No âmbito individual, 21% das crianças não apresentaram mudanças na QVRS, foi observada melhora em 40% e agravamento em 38% dos casos. Deficiência grave antes da admissão (escore global do HUI3 < 0,70) esteve presente em 36% dos casos, com melhora no seguimento aos 6 meses em 60% deles. Entre aqueles que apresentaram agravamento da QVRS no seguimento, 45% eram vítimas de trauma.Conclusões: Embora a QVRS seja globalmente semelhante nas duas avaliações, foram encontradas várias diferenças no âmbito individual. As crianças com baixa QVRS antes da admissão (deficiência grave) podem se beneficiar da terapia intensiva pediátrica, visto que muitas dessas crianças melhoraram a QVRS, em comparação com seu estado pré-admissão. J Pediatr (Rio J)

Epidemiology of Intensive Care Admissions for Children in the US From 2001 to 2019

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Colorful, Cute, Attractive and Carcinogenic: The Dangers of Dyes

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