Use of the skin prick test and specific immunoglobulin E for the diagnosis of cockroach allergy

Lopes, Maria Isabella L.; Miranda, Paulo Henrique Oliveira de; Sarinho, Emanuel

doi:10.2223/jped.1487

Cited by 23 publications

(23 citation statements)

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“…Sensitization to cockroaches was demonstrated to be a risk factor for greater severity of the disease. 25 In our study, we found sensitization to Periplaneta americana in 8.5% of the patients and German cockroaches in 6.4% of the patients.…”

Section: Discussionsupporting

confidence: 48%

Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

et al. 2013

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CONTEXT AND OBJECTIVE: Knowledge of the profile of allergen sensitization among children is important for planning preventive measures. The objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of Palmas. DESIGN AND SETTING: Cross-sectional study at outpatient clinics in Palmas, Tocantins, Brazil. METHODS: Ninety-four patients aged 1-15 years who were attending two pediatric outpatient clinics were selected between September and November 2008. All of the subjects underwent clinical interviews and skin prick tests. RESULTS:A positive skin prick test was observed in 76.6% of the participants (72.3% for inhalants and 28.9% for food allergens). The most frequent allergens were Dermatophagoides pteronyssinus (34%), cat epithelium (28.7%), dog epithelium (21.3%), Dermatophagoides farinae (19.1%), Blomia tropicalis (18.1%), cow's milk (9.6%) and grasses (9.6%). A positive skin prick test correlated with a history of atopic disease (odds ratio, OR = 5.833; P = 0.002), a family history of atopic disease (OR = 8.400; P < 0.001), maternal asthma (OR = 8.077; P = 0.048), pet exposure (OR = 3.600; P = 0.012) and cesarean delivery (OR = 3.367; P = 0.019). CONCLUSION: Dermatophagoides pteronyssinus was the most frequent aeroallergen and cow's milk was the most prevalent food allergen. There was a positive correlation between a positive skin prick test and several factors, such as a family history of atopic disease, maternal asthma, pet exposure and cesarean delivery.RESUMO CONTEXTO E OBJETIVO: O conhecimento sobre o perfil da sensibilização a alérgenos em crianças é importante para o planejamento de medidas preventivas. O objetivo deste estudo foi avaliar a prevalência e perfil de sensibilização a alérgenos inalados e alimentares em crianças e adolescentes em uma população ambulatorial na cidade de Palmas. TIPO DE ESTUDO E LOCAL: Estudo transversal em unidades ambulatoriais em Palmas, Tocantins, Brasil. MÉTODOS: Foram selecionados 94 pacientes com idades entre 1 a 15 anos em 2 ambulatórios de pediatria entre setembro e novembro de 2008. Todos os sujeitos foram submetidos a entrevistas clínicas e testes cutâneos de puntura. RESULTADOS: Um teste cutâneo de puntura positivo foi observado em 76,6% dos participantes (72,3% para inalantes, 28,9% para alérgenos alimentares). Os alérgenos mais frequentes foram Dermatophagoides pteronyssinus (34%), epitélio de gato (28,7%), epitélio de cão (21,3%), Dermatophagoides farinae (19,1%), Blomia tropicalis (18,1%), leite de vaca (9,6%) e gramíneas (9,6%). Um teste cutâneo de puntura positivo foi relacionado à história de doença atópica (razão de chances RC = 5,833, P = 0,002), história familiar de atopia (RC = 8,400, P < 0,001), asma materna (RC = 8,077, P = 0,048), exposição a animal de estimação (RC = 3,600, P = 0,012) e parto cesáreo (RC = 3,367, P = 0,019). CONCLUSÃO: Dermatophagoides pteronyssinus foi o aeroalérgeno mais prevalente e, dentre alérgenos a...

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Section: Discussionsupporting

confidence: 48%

Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

et al. 2013

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“…Almanya Dresden'de çocuklarda prevalans %4 bulunurken; İtalya'da okulöncesi çocuklarda duyarlaşma prevalansı %0.45 olarak saptanmıştır (25). Astımlı olmayanlar çocuklar Alman hamamböceğine (%4.8) ve Amerikan hamamböceğine göre (%2.4) daha duyarlı bulunmuştur (26). ABD Washington eyaletinde 253 sağ-lıklı kontrolde yapılan araştırmada katılımcılarda %7.5 oranında duyarlılık saptanmıştır (27).…”

Section: Hamamböceği Duyarlığının Değişik Toplumlardaki Normal Prevalunclassified

Cockroach Allergy and Its Immunotherapy

Özdemir

Aydın

2016

Asthma Allergy Immunol

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ÖZHamamböceği allerjisi 30 yılı aşkın süredir, solunum yolu allerjik hastalıklarının önemli bir nedeni olarak düşünülmektedir. En sık evcil hamamböceği türleri Alman (Blattella germanica) ve Amerikan (Periplaneta americana) hamamböcekleridir. Alman hamamböceği küçük, 16 mm boyunda, tüm dünyada evlerde bulunan bir böcektir. Amerikan hamamböceği daha büyük, 35-53 mm boyutunda, ev, hastane, okul ve diğer büyük binalarda da bulunabilen bir böcektir. Türkiye' de 20' den fazla hamamböceği türü olmasına rağmen, en sık Alman hamamböceğine rastlanır. ABD' de çocuk ve erişkinleri içeren değişik araştırmalarda hamamböceği allerjisi %17-41 arasında bulunmuştur. Avrupa' da allerji kliniğine başvuran çocuk ve erişkinlerde yapılan çalışmalarda ise, %4-26 oranında saptanmıştır. Türkiye' de hamamböceği allerjisi prevalansı çocuk ve erişkinleri içeren değişik araştırmalarda %2.2-51.4 arasında bildirilmiştir. Tropomyosin, Bla g7 ve Per a7 denilen, hamamböceklerindeki major allerjenlerden biridir. Ayrıca tropomyosin, böceklerle omurgasızlar (akar, kabuklular, yumuşakca ve parazitler) arasındaki çapraz reaktivitede rol oynayan bir allerjendir. Hamamböceğine duyarlı kişilerde, diğer omurgasızların allerjenlerine kosensitizasyon yaygın bir özelliktir. Böylece, parazit enfestasyonları çapraz reaktif antikorlar aracılığıyla allerjik reaktiviteyi regüle ederler. Hamamböceği allerjen düzeyini tamamen başarılı bir temizlikten sonrası bile sürekli düşük tutmak zor olmasına ilaveten, hamamböceği allerjisinin teşhis ve tedavisinde kullanılan ticari ekstraktlar standardize değildirler. Bazı çalışmalar hamamböceğine karşı immünoterapinin etkili olduğunu düşündürmesine rağmen; kaliteli ekstraktlar, daha çok sayıda ve daha uzun süre takip edilen hastalar ile yapılacak randomize kontrollü çalışmalar bu tedavinin etkinlik ve güvenilirliğini göstermek için gereklidir. ABSTRACTCockroach allergy has been considered as an important cause of respiratory allergic diseases for over three decades. The most common domiciliary cockroach species are Blattella germanica (German cockroach) and Periplaneta americana (American cockroach). Blattella germanica is a small cockroach, approximately 16 mm in length, which commonly infests houses worldwide. Periplaneta americana is a large cockroach, approximately 35-53 mm in length, that infests houses, schools, hospitals, and other large buildings. There are more than 20 different cockroach species in Turkey, and Blattella germanica is known as the most common. In the United States, the prevalence of cockroach allergy ranges from 17 to 41%'in various studies involving both children and adults. European studies on children and adults attending an allergy clinic show a high variability in cockroach sensitisation varying from %4-26. In Turkey, cockroach allergy prevalence rate varies from %2.2-51.4 in different studies consisting of both children and adults. Tropomyosin, designated as Bla g7 and Per a7, has been identified as a major allergen in cockroaches. Tropomyosin is also an important allergen involved in cross-rea...

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“…1 Cockroach allergy has been known for over 40 years and, since then, studies have been carried out worldwide, showing the association between the development of specific IgE antibodies against cockroach allergens and asthma. Despite this fact, even in the USA, where most of the research on this topic is conducted, parents or surrogates of asthmatic children associate the cause of asthma attacks with tobacco smoke, fungi, dust, and inhaled irritants, but not with cockroaches.…”

Section: Dear Editormentioning

confidence: 99%

“…1 In most diabetic patients, celiac disease (CD) is insidious and asymptomatic; therefore, serological screening for CD is crucial for an early diagnosis and introduction of appropriate treatment. 2 In a cross-sectional study, Araújo et al 1 found a prevalence of 10.5% for CD among children and adolescents with type 1 diabetes mellitus (DM-1) using the anti-tissue transglutaminase (anti-tTG) antibody assay, recommended as the test of choice for the initial screening of CD in diabetic patients. 3 Serological tests for the detection of anti-tTG and antiendomysial antibodies should be reserved for IgA isotypes; therefore, it is necessary to identify patients with IgA deficiency (IgAD) beforehand in order to rule out false-negative results.…”

Section: Dear Editormentioning

confidence: 99%

“…Therefore, it is quite likely that: a) more than a direct effect on lungs, the action of allergenic proteins may result from immediate and late allergic reactions and b) even though they act as triggers of asthma attacks, allergens per se are the main cause of inflammation that coexists with asthma in individuals who are genetically susceptible to atopic disease. 1 For some decades, it has been known that household dust and mites may cause atopic sensitization, with the development of different clinical symptoms. Among those aeroallergens that play a role in the pathogenesis of respiratory allergies, one should pay special attention to those produced by fungi, cockroaches, pollen, and pet dander.…”

mentioning

confidence: 99%

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Alergia a baratas: fator de risco para asma de maior gravidade

Camelo-Nunes¹,

Solé²

2006

J. Pediatr. (Rio J.)

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Use of the skin prick test and specific immunoglobulin E for the diagnosis of cockroach allergy

Abstract: Allergic sensitivity to cockroaches was a predictive factor for asthma severity. The skin prick test is more appropriate for the detection of clinically relevant sensitivity to cockroaches than specific IgE determination.

Cited by 23 publications

References 24 publications

Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

Cockroach Allergy and Its Immunotherapy

Alergia a baratas: fator de risco para asma de maior gravidade

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