Body composition and nutritional and metabolic parameters in postmenopausal women sufficient, insufficient and deficient in vitamin D

Abstract

Objective: We investigated changes in body composition and nutritional and metabolic parameters in a group of postmenopausal women who were classified as sufficient, insufficient and deficient in vitamin D. Subjects and methods: A total of 106 postmenopausal women were included in this cross-sectional study and classified according to their serum levels of 25-OH-vitamin D as sufficient (≥ 30 ng/mL; group S), insufficient (20.1 and 29.9 ng/mL; group I) or deficient (≤ 20 ng/mL; group D) in vitamin D. Body composition was measured by dual-energy X-ray absorptiometry (DXA); dietary recall questionnaires were completed; and blood samples were analysed to compare the metabolic and nutritional status of the study groups. Results: Eleven (10.4%) of the women were classified in group S, 50 (47.2%) in group I and 45 (42.4%) in group D, with a mean serum level for 25-OH-D of 21.1 ± 7.0 ng/mL in all participants. Body composition did not differ among the groups. Serum levels of 25-OH-D were negatively correlated with serum levels of triglycerides, total cholesterol and LDL cholesterol. Conclusions: Vitamin D insufficiency and deficiency were highly prevalent in our group of postmenopausal women, showing an association with an unfavourable lipid profile.

Relação entre vitamina D e distúrbios metabólicos em mulheres menopausadas

“…No grupo amostral, notou-se que há forte relação na associação da vitamina D com os níveis de LDL e colesterol, sendo um dos parâmetros também vislumbrados em demais estudos. Como exemplo, têm-se uma pesquisa feita com 106 mulheres pós-menopausadas do Paraná, na qual se obteve correlação inversa entre os valores de vitamina D em relação aos níveis séricos de colesterol total, LDL-colesterol e triglicérides, o que reforça perfil lipídico desfavorável para mulheres com insuficiência de 25(OH) (SIMAS LAW et al, 2019). No entanto, nela obteve-se correlação negativa em relação a estrutura corporal, bem como foi possível analisar no presente trabalho, uma vez que a relação de IMC e circunferência corporal, não obteve relação satisfatória.…”

Association between Body Fatness and Vitamin D3 Status in a Postmenopausal Population

“…In studies carried out of menopause, low levels of vitamin D were associated with a higher frequency of clinical fractures and low bone mass [21], in addition to the percentage of postmenopausal women with osteoporosis being higher in those with vitamin D deficiency [22]. During menopause, it has been shown that women may be particularly susceptible to the consequences of vitamin D deficiency, since a decrease in bone mineral density (BMD) and lean mass, as well as an increase in fat mass, occurs [23] in this period of life as a result of the decrease in estrogen levels.…”