ABSI is a poor predictor of insulin resistance in Chinese adults and elderly without diabetes

Abstract

Objective: Recently, a new obesity index (A Body Shape Index, ABSI) based on waist circumference (WC) was developed, and high ABSI corresponds to a more central concentration of body volume. It is well known that central obesity is closely linked with insulin resistance (IR). Therefore, our study aimed to examine the discriminatory power of ABSI for IR in Chinese adults and elderly without diabetes. Subjects and methods: In 2007, a cross-sectional study was made. In this study, 570 individuals without diabetes were available for analysis (male: 56.1%, mean age: 62.3 ± 6.5 years). Insulin resistance was assessed by homeostasis model assessment (HOMA-IR). Areas under the receiver operating characteristic (ROC) curves were determined to identify variables/models that could predict insulin resistance. Results: ABSI was associated with IR, the cutoff points was 0.0785 m11/6kg-2/3 to identifying IR and the area under the ROC (AUC) curve was 0.618 (95%CI: 0.561-0.675), which was not better than body mass index BMI (AUC = 0.753; 95%CI: 0.706-0.801), WC (AUC = 0.749; 95%CI: 0.700-0.797), and fasting plasma glucose (FPG, AUC = 0.752; 95%CI: 0.705-0.799). Furthermore, combination with ABSI could improve the discriminatory power of other variables for IR. The AUC curve increased from 0.753 to 0.771for BMI, 0.749 to 0.754 for WC, 0.752 to 0.769 for FPG, respectively. Conclusions: ABSI is associated with IR in the general Chinese adults and elderly without diabetes, but the discriminatory power for IR is poor. It is recommended that ABSI be used in combination with other variables.

Sex-Specific Differences in the Relationship between Insulin Resistance and Adiposity Indexes in Children and Adolescents with Obesity

“…In this study, ABSI was not correlated with IR indexes, showing that this parameter is a poor predictor of IR [46]. Bouchi et al have reported that ABSI related to abdominal vs. peripheral fat ratio is positively correlated with visceral adipose depot and is supposed to be BMI-independent [47].…”

Comparisons of conventional and novel anthropometric obesity indices to predict metabolic syndrome among vegetarians in Malaysia

“…In the present study, we found that ABSI was useful to predict MetS in female, but not in male vegetarians. Previous studies conducted in Spain concluded that ABSI should not be used to predict MetS 37 and insulin resistance in China 35 . The mean difference in the individual height could impact the ability of ABSI to determine the MetS 37 .…”

“…Another thing to be highlighted is ABSI is derived based on the American population 32 . Since Asians were at greater risk of abdominal obesity and low muscle mass than Caucasians, it is therefore the coefficients of ABSI that derived from American population might not be applicable to other population, especially for Asian populations 35 . On the other hand, BRI was the poor index to identify MetS in both sexes, which is similar to the previous research in Poland 17 .…”

Subclinical Hypothyroidism Represents Visceral Adipose Indices, Especially in Women With Cardiovascular Risk

“…Some studies have found there is a positive correlation between ABSI and disease risk and mortality hazard [ 39 , 40 ]. However, other studies have obtained opposite results [ 36 , 41 ].…”