Bouts of exercise elicit discordant testosterone: cortisol ratios in runners and non-runners

Abstract

A biphasic time-profile in the testosterone:cortisol ratio can be seen in short-bout, high intensity exercise (treadmill running) during the morning in men trained for this specific physical activity.

Physical Training Increases Erythroferrone Levels in Men

“…Each bout of physical exercise contributes to the release of noradrenaline, cortisol, and androgens [ 28 , 29 , 30 , 31 ], which are hormones that stimulate the secretion of EPO, which, in turn, leads to the increased erythropoietic activity of the bone marrow [ 5 ]. Testosterone can also directly affect erythroblasts by increasing the number of receptors for EPO [ 28 , 29 , 30 , 31 ].…”

“…Each bout of physical exercise contributes to the release of noradrenaline, cortisol, and androgens [ 28 , 29 , 30 , 31 ], which are hormones that stimulate the secretion of EPO, which, in turn, leads to the increased erythropoietic activity of the bone marrow [ 5 ]. Testosterone can also directly affect erythroblasts by increasing the number of receptors for EPO [ 28 , 29 , 30 , 31 ]. Current data have also revealed the complex interaction of noradrenaline within the bone marrow, and thus the dependence of the erythropoietic response on the intensity and duration of exercise and the associated stress response [ 28 , 29 , 30 , 31 ].…”

“…Testosterone can also directly affect erythroblasts by increasing the number of receptors for EPO [ 28 , 29 , 30 , 31 ]. Current data have also revealed the complex interaction of noradrenaline within the bone marrow, and thus the dependence of the erythropoietic response on the intensity and duration of exercise and the associated stress response [ 28 , 29 , 30 , 31 ]. Review studies indicate that short-term exercise does not significantly affect EPO levels, while prolonged, intense physical effort (such as ultramarathon runs) leads to a temporary increase in EPO levels, both in trained and untrained men [ 4 , 31 ].…”