1989
DOI: 10.1677/joe.0.1230099
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Abstract: Changes in the amount of cytosolic 3,5,3'-tri-iodo-L-thyronine (T3)-binding protein (CTBP) and its activator during administration of L-thyroxine (T4) to thyroidectomized rats were investigated. Thyroidectomy decreased the amount of CTBP in the kidney, whereas the activator was not significantly modified by thyroidectomy. The activator was increased by administration of T4 to thyroidectomized rats. The amount of CTBP was also increased by administration of T4. The activator increased the maximal binding capaci… Show more

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Cited by 10 publications
(3 citation statements)
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“…Previously we observed that the level of CTBP was decreased by thyroidectomy in rat kidney. The level was restored by the administration of T4 without changes in the affinity constant for T3 binding [7]. These results indicated that CTBP is one of the thyroid hormone responsive proteins.…”
mentioning
confidence: 72%
“…Previously we observed that the level of CTBP was decreased by thyroidectomy in rat kidney. The level was restored by the administration of T4 without changes in the affinity constant for T3 binding [7]. These results indicated that CTBP is one of the thyroid hormone responsive proteins.…”
mentioning
confidence: 72%
“…In studies with rats, the MBC obtained in the presence of NADPH increased during the growth of animals, and a tissue-specific increase was observed (12,13). Cellular levels of the protein could be increased by thyroid hormone, vitamin D3 and insulin in vitro (14)(15)(16)(17). Dexamethasone increases the mRNA of CTBP in cultured human myeloblasts (18).…”
Section: Introductionmentioning
confidence: 96%
“…Hepatic CTBP was also deter¬ mined for the following reasons: 1. CTBP is regulated by thyroid hormone (Nishii et al 1989) and serves as a marker of thyroid hormone action. 2.…”
Section: Introductionmentioning
confidence: 99%