A microsurgical technique for catheter insertion in the rat femoral artery

Sugai, Kazuhisa; Hakamata, Yoji; Tamura, Tomoyoshi; Kataoka, Masaharu; Fujisawa, Masahiko; Sano, Motoaki; Kobayashi, Eiji

doi:10.1590/s0102-865020200100000004

Cited by 2 publications

(2 citation statements)

References 15 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We dissected out the vein that collects blood from the upper jejunal mucosa on the anus side from the tip of the percutaneous gastrostomy tube (jejunal vein) and placed an 18-gauge (18G) central venous (CV) catheter (outer diameter [OD], 1.1 mm) in the direction of the intestine by using our previously developed curved needle guide method [ 12 ]. To enable changes in H 2 concentration to be monitored in real time, we ensured that the tip of the catheter would not cause congestion in the venous arc ( Figure 1 B).…”

Section: Methodsmentioning

confidence: 99%

Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs

Ichihara

Katsumata

Moriyama

et al. 2021

Heliyon

Self Cite

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs

Ichihara

Katsumata

Moriyama

et al. 2021

Heliyon

Self Cite

View full text Add to dashboard Cite

“…An incision of approximately 1.5 cm was made and the left femoral artery was exposed. A telemetric transmitter (HD-S10, Physiotel HD Telemetry, Data Science International, St. Paul, MN, USA) catheter was inserted into the left femoral artery 38 . The tip of the transmitter catheter was placed in the abdominal aorta caudally from the renal artery bifurcation.…”

Section: Development Of H 2 Inhalation Apparatusmentioning

confidence: 99%

Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

Sugai

Tamura

Sano

et al. 2020

Sci Rep

Self Cite

View full text Add to dashboard Cite

A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H2) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H2 has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H2 (1.3% H2 + 21% O2 + 77.7% N2) or control (21% O2 + 79% N2) gas mixture for 1 h per day. H2 significantly suppressed increases in blood pressure after 5/6 nephrectomy. The anti-hypertensive effect of H2 was also confirmed in rats in a stable hypertensive state 3 weeks after nephrectomy. To examine the detailed effects of H2 on hypertension, we used an implanted telemetry system to continuously monitor blood pressure. H2 exerted an anti-hypertensive effect not only during daytime rest, but also during night-time activities. Spectral analysis of blood pressure variability revealed that H2 improved autonomic imbalance, namely by suppressing the overly active sympathetic nervous system and augmenting parasympathetic nervous system activity; these effects co-occurred with the blood pressure-lowering effect. In conclusion, 1-h daily exposure to H2 exerts an anti-hypertensive effect in an animal model of hypertension.

show abstract

A microsurgical technique for catheter insertion in the rat femoral artery

Abstract: Conception and design of the study, analysis and interpretation of data, manuscript writing.

Cited by 2 publications

References 15 publications

Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs

Pharmacokinetics of hydrogen after ingesting a hydrogen-rich solution: A study in pigs

Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

Contact Info

Product

Resources

About