2019
DOI: 10.1590/s0102-865020190060000007
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Abstract: Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the objective of the present study was to investigate the effect of its use for pretreatment of partially hepatectomized rats. Methods The animals were divided into tw… Show more

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Cited by 1 publication
(4 citation statements)
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References 15 publications
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“…Three animals remained in each box with free access to tap water. All animals were allowed to acclimatize for a week, followed by randomization and allocation (8)(9)(10)(11)(12) . There were two groups (n=12): rutin group (G1) received suspension 40 mg rutin /kg/day for 10 days, prior to the performance of partial hepatectomy, administered orally (gastric gavage).…”
Section: Methodsmentioning
confidence: 99%
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“…Three animals remained in each box with free access to tap water. All animals were allowed to acclimatize for a week, followed by randomization and allocation (8)(9)(10)(11)(12) . There were two groups (n=12): rutin group (G1) received suspension 40 mg rutin /kg/day for 10 days, prior to the performance of partial hepatectomy, administered orally (gastric gavage).…”
Section: Methodsmentioning
confidence: 99%
“…The removal of almost 70% of the liver tissue was performed after a 12-hour fast and administering anesthesia with high dose of xylazine and ketamine solution via intraperitoneal (8)(9)(10)(11)(12) . A sensitivity test was performed on the lower and upper limbs before the start of the surgical procedure.…”
Section: Partial Hepatectomy Sample Collection Euthanasia and Histomentioning
confidence: 99%
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