2018
DOI: 10.1590/s0102-865020180080000008
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: It is well known that during hepatic operative procedures, it is often critical that the irrigation is interrupted to avoid possible bleeding, blood transfusions, variable intensities, and their short and long-term consequences. It was believed in the past that the flow interruption should not exceed 20 minutes, which limited the use of this maneuver. However, it has been postulated that ischemia could be maintained for more than 60 minutes in healthy livers. The present paper review includes: 1) A brief intro… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
35
0
3

Year Published

2018
2018
2023
2023

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 39 publications
(38 citation statements)
references
References 40 publications
(53 reference statements)
0
35
0
3
Order By: Relevance
“…Hepatic I/R is a complex process involving a variety of cell types, molecular pathways, and mediators. Previous investigations have suggested that regulated cell death, such as apoptosis and necroptosis, plays a role in the process of hepatic I/R injury; however, the contribution of apoptosis and necroptosis to hepatic I/R injury is still controversial. With respect to apoptosis, since hepatic I/R injury is generally accompanied by inflammation, it is unlikely that apoptosis contributes to hepatic I/R injury.…”
Section: Discussionmentioning
confidence: 99%
“…Hepatic I/R is a complex process involving a variety of cell types, molecular pathways, and mediators. Previous investigations have suggested that regulated cell death, such as apoptosis and necroptosis, plays a role in the process of hepatic I/R injury; however, the contribution of apoptosis and necroptosis to hepatic I/R injury is still controversial. With respect to apoptosis, since hepatic I/R injury is generally accompanied by inflammation, it is unlikely that apoptosis contributes to hepatic I/R injury.…”
Section: Discussionmentioning
confidence: 99%
“…Biochemical and metabolic events, functional disorders and morphological findings have been associated with the functional alterations observed during I/R due to necrosis and apoptosis involved in cell death 5,[15][16][17] . In the present study, we used the aminotransferases (ALT, AST), ALP and albumin to evaluate the hepatic injury degree.…”
Section: Discussionmentioning
confidence: 99%
“…The necrotic cells morphology is characterized by increased eosinophilia, cytoplasm vacuoles, cellular edema and membranes ruptures with intracellular contents extravasation, causing inflammation and aggression of adjacent healthy tissues 5,15 . In our study, the necrosis degree was evaluated semi-quantitatively and graded from 0 to The electromagnetic fields influence has been studied by some scientists which related the interaction of MF with ion channels, oxidative stress and physical structure of water 7,12,20 suggesting a better fluidity of the aqueous solution and consequently a potentiation of ischemia process hydration.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations