2018
DOI: 10.1590/s0102-865020180050000004
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Abstract: Effect of red propolis on hamster cheek pouch angiogenesis in a new sponge implant model 1 Abstract Purpose: To evaluate the effects of red propolis on cheek pouch angiogenesis in a hamster new model sponge implant. Methods: Forty eight animals divided into eight groups. (Groups I-IV), the animals were treated for 15 days before and 10 days after sponge implantation. (Groups V-VIII), the animals were treated for 10 days after sponge implantation (GI and GV: red propolis 100 mg/kg, GII and GVI: celecoxib 20 mg/… Show more

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Cited by 5 publications
(5 citation statements)
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“…In earlier experiments on animal models conducted by our team, red propolis inhibited inflammatory and neoplastic angiogenesis associated with a reduction in inflammatory cells (e.g., mastocytes and macrophages) suggestive of immunomodulatory action 26 , 27 .…”
Section: Discussionmentioning
confidence: 70%
“…In earlier experiments on animal models conducted by our team, red propolis inhibited inflammatory and neoplastic angiogenesis associated with a reduction in inflammatory cells (e.g., mastocytes and macrophages) suggestive of immunomodulatory action 26 , 27 .…”
Section: Discussionmentioning
confidence: 70%
“…The findings on propolis' actions regarding neovascularization and angiogenesis have shown contradicting results. In some studies, propolis positively affects angiogenesis (Abdel-Wahed et al, 2013;Nindra et al, 2021;Staniczek et al, 2021;Sungkar et al, 2021), and in other studies it negatively affects angiogenesis (Chikaraishi et al, 2010;Lima et al, 2014;Melo et al, 2018). Sungkar et al (2021) reported that EEP from Mount Lawu, Indonesia has angiogenic effects or promotes angiogenesis through decreased malondialdehyde blood levels and IL-6 blood levels, and an increase in vascular endothelial growth factor (VEGF) blood levels.…”
Section: Stimulation Of Angiogenesis and Neovascularizationmentioning
confidence: 99%
“…The findings on propolis' actions regarding neovascularization and angiogenesis have shown contradicting results. In some studies, propolis positively affects angiogenesis (Abdel‐Wahed et al, 2013; Nindra et al, 2021; Staniczek et al, 2021; Sungkar et al, 2021), and in other studies it negatively affects angiogenesis (Chikaraishi et al, 2010; Lima et al, 2014; Melo et al, 2018).…”
Section: Wound Healing Effects Of Propolismentioning
confidence: 99%
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“…Complement, lymphocyte and macrophage activation has been observed in many studies, suggesting they are part of the mechanism by which propolis induces apoptosis in tumor cells. ( 11 13 ) In this way, we therefore included an experiment with 33 days of treatment with propolis prior to inoculation (experiment 2).…”
Section: Introductionmentioning
confidence: 99%