2018
DOI: 10.1590/s0102-865020180040000003
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Abstract: Dexmedetomidine can decrease blood pressure and heart rate in rabbits in a dose-dependent manner, but there is no effect on the myocardial systolic and diastolic function.

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Cited by 11 publications
(5 citation statements)
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“…Although quite a few studies have con rmed the bene cial effects of intravenous or epidural infusion of dexmedetomidine on the management of perioperative patients, the hemodynamic effects of dexmedetomide also cannot be ignored. The conclusions of previous studies 6 ; 12 have determined that dexmedetomidine can inhibit perioperative hemodynamics in patients to a certain extent, which is consistent with the results of the present study.…”
Section: Discussionsupporting
confidence: 93%
“…Although quite a few studies have con rmed the bene cial effects of intravenous or epidural infusion of dexmedetomidine on the management of perioperative patients, the hemodynamic effects of dexmedetomide also cannot be ignored. The conclusions of previous studies 6 ; 12 have determined that dexmedetomidine can inhibit perioperative hemodynamics in patients to a certain extent, which is consistent with the results of the present study.…”
Section: Discussionsupporting
confidence: 93%
“…In this study, we established the rat model of extensive myocardial injury by subcutaneous injection of ISO at a dose of 170 mg/kg for 2 consecutive days. The changes of hemodynamic parameters often used to evaluate the heart function [23,24]. Two weeks later, our results showed that in comparison with the control group, the left ventricular function reduced in the groups received ISO injection (P <0.05).…”
Section: Discussionmentioning
confidence: 57%
“…In this study, we established the rat model of extensive myocardial injury by subcutaneous injection of ISO at a dose of 170 mg/kg for 2 consecutive days. The changes of hemodynamic parameters often used to evaluate the heart function [23,24]. Two weeks later, our results showed that in comparison with the control group, the left ventricular function reduced in the groups received ISO injection (P <0.05).…”
Section: Discussionmentioning
confidence: 57%