End-to-side versus end-to-end neurorrhaphy at the peroneal nerve in rats

Viterbo, Fausto; Brock, Ryane Schmidt; Maciel, Fábio Oliveira; Ayestaray, Benoît; Garbino, José Antônio; Rodrigues, Cecília Pessoa

doi:10.1590/s0102-865020170090000002

Cited by 15 publications

(5 citation statements)

References 27 publications

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“…The present study has some limitation: It was not evaluated the sensory and mixed nerve conduction 8,15 and in surgical post-operation (end-to-end 9 , 15 , end-to-side 8 , 11 , 16 and side-to-side 17 neurorrhaphy). If the study had been conducted in this scenario, the electrode’s type could affect the results.…”

Section: Discussionmentioning

confidence: 93%

Does the type of electrode affect the electromyoneurographic parameters in rats?

et al. 2019

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Purpose To evaluate if the type of electrode (needle vs. surface) affects the electromyoneurography parameters in rats. Methods Twenty male rats were anesthetized, then compound muscle action potential were recorded using a Neuropack S1 MEB- 9400 © . All animals were submitted to two electroneuromyography analysis: first with surface electrode and then by needle electrode. We evaluated the latency, amplitude, duration and area of the negative peak of the gastrocnemius and cranial tibial muscles. Results There were no significant differences between the groups in the mean of duration, latency, amplitude or area of the negative peak in gastrocnemius and cranial tibial muscles. Conclusion The type of electrode does not affect the electroneuromyography parameters.

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Section: Discussionmentioning

confidence: 93%

Does the type of electrode affect the electromyoneurographic parameters in rats?

et al. 2019

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“…ETS coaptation results in inferior neural penetration to the recipient branch compared with end-to-end coaptation. Some studies demonstrated similar functional results in ETS and end-to-end coaptations (Lutz et al, 2000;Viterbo et al, 2017). Others suggest that unlike sensory axons, motor axons regenerate only in response to a deliberate injury (Pannucci et al, 2007;Tos et al, 2009).…”

Section: Discussionmentioning

confidence: 93%

Does supercharging with cross‐face nerve graft enhance smile in non‐flaccid facial paralysis patients undergoing selective neurectomy?

Kaufman Goldberg,

Trzcinski,

McGonagle

et al. 2023

Microsurgery

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BackgroundCross face nerve grafting (CFNG) is a well‐established nerve transfer technique in facial reanimation; however, no study has assessed outcome of supercharging the smile with CFNG in patients with synkinesis. The goal of this study was to examine the smile outcome in non‐flaccid facial paralysis (NFFP) patients after supercharging with CFNG during selective neurectomy.MethodsNFFP patients who underwent CFNG with end‐to‐side coaptation to a smile branch on the paralyzed side during selective neurectomy were retrospectively identified and their charts were reviewed. Pre‐operative and post‐operative facial function was assessed with the electronic clinician‐graded facial function tool (eFACE), and an automated computer‐aided facial assessment tool (Emotrics). Smile metrics were compared pre‐operatively, in early post‐operative time (EPO, <6 months), and late post‐operative time (LPO, >9 months) when CFNG contribution would be expected.ResultsThirteen cases were performed between June 2019 and December 2021. No objective smile metrics improved following supercharging with CFNG. Oral commissure excursion improved by 1.23 points in eFACE (p = .812), and by 0.84 in Emotrtics (p = .187) from EPO to LPO. EFACE dynamic score was improved by 0.08 points from EPO to LPO (p = .969).ConclusionsUsing CFNG for supercharging the smile during selective neurectomy in NFFP patients may not enhance smile. Longer term results following supercharging and long term natural history of selective neurectomy should be assessed.

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“…Yu et al (2017) report that the end‐to‐side nerve repair of a sensory nerve induces a successful motor nerve reinnervation. On the other hand, there is an article reporting no functional or histological differences among the end‐to‐side, side‐to‐end, and end‐to‐end techniques for neurrorhaphy (Viterbo et al, 2017). This study performed end‐to‐side neurorrhaphy between the mandibular branch and the hypoglossal nerve with 40% neurectomy in the first‐stage operation and confirmed no marked impairment of function due to neurectomy.…”

Section: Discussionmentioning

confidence: 99%

Prevention of denervated muscle atrophy with accelerated nerve‐regeneration by babysitter procedure in rat facial nerve paralysis model

et al. 2020

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Purpose The “babysitter” procedure is a reconstruction technique for facial nerve complete paralysis and uses the movement source from the healthy facial nerve with a cross‐nerve graft. First, an end‐to‐side neurorrhaphy is performed between the affected facial nerve trunk and hypoglossal nerve for continuously delivering stimuli to the mimetic muscles for preventing the atrophy of mimetic muscles. Despite favorable clinical results, histological and physiological mechanisms remain unknown. This study attempted to establish a model for the “babysitter” procedure and find its efficacy in rats with facial nerve complete paralysis. Materials and Methods A total of 16 Lewis rats were used and divided into 2 groups; cross nerve graft (n = 8) and babysitter groups (n = 8). The facial nerve trunk was transected in both groups. Babysitter group underwent a two‐stage procedure. Cross nerve graft group underwent only the transfer of nerve graft from the healthy side to affected side. The animals were assessed physiologically by compound muscle action potential (CMAP), and the regenerated nerve tissues were evaluated histopathologically at 13 weeks after surgery. Results Facial nucleus stained with retrograde tracers proved the re‐innervation of affected facial muscle by the babysitter procedure. In CMAP, the amplitude of babysitter group was significantly higher than that of the cross‐facial nerve graft group (p < .05). Histological examination found a significant difference in myelin g‐ratio between two groups (p < .05). Conclusion This study investigated the “babysitter” procedure for rat facial nerve palsy. Babysitter procedure shortened the denervation period without mimic muscle atrophy.

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End-to-side versus end-to-end neurorrhaphy at the peroneal nerve in rats

Cited by 15 publications

References 27 publications

Does the type of electrode affect the electromyoneurographic parameters in rats?

Does the type of electrode affect the electromyoneurographic parameters in rats?

Does supercharging with cross‐face nerve graft enhance smile in non‐flaccid facial paralysis patients undergoing selective neurectomy?

Prevention of denervated muscle atrophy with accelerated nerve‐regeneration by babysitter procedure in rat facial nerve paralysis model

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