2017
DOI: 10.1590/s0102-865020170050000001
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Abstract: 325Doppler velocimetry in fetal rats exposed to enoxaparin and unfractionated heparin (UFH) during pregnancy Senefonte FRA et. al. Acta Cir Bras. 2017;32(5):325-333

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Cited by 3 publications
(3 citation statements)
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“…Other studies have also proved that omega improved uterine artery perfusion in non-pregnant patients [22]. Importantly, animal models treated with heparin also recorded reduced uterine artery resistance and pulsatility indices [23]. Thus, ASA+omega association with heparin appears to play a key role in reducing these indices, in optimizing uterine flow and in providing good oxygen supply to the fetus.…”
Section: Discussionmentioning
confidence: 87%
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“…Other studies have also proved that omega improved uterine artery perfusion in non-pregnant patients [22]. Importantly, animal models treated with heparin also recorded reduced uterine artery resistance and pulsatility indices [23]. Thus, ASA+omega association with heparin appears to play a key role in reducing these indices, in optimizing uterine flow and in providing good oxygen supply to the fetus.…”
Section: Discussionmentioning
confidence: 87%
“…This outcome is encouraging and interesting because it allows reasoning about the role played by omega as antioxidant and in reducing inflammatory processes to facilitate placentation and to enable good placental flow for proper fetal growth [1,20]. Such omega performance has been investigated and cited in several studies [21][22][23]. According to a study conducted in Egypt in 2016, omega has successfully increased the amount of amniotic fluid in patients presenting unexplained oligohydramnios.…”
Section: Discussionmentioning
confidence: 94%
“…Modern studies have also proved that systematic application of Doppler ultrasound can reduce the perinatal mortality of pregnancy with late placental insufficiency by about 50% [48] . Doppler ultrasound was a procedure chosen before and after drugs administration, which was used to monitor the fetal placental blood circulation parameters to judge the efficacy of the placental insufficiency drugs (LMWH, FRT, and LMWH + FRT), and to prevent adverse fetal and maternal outcomes [49] . Doppler ultrasound has shown the precise effect in the diagnosis, surveillance, and prognosis of pregnancies complicated placental insufficiency [50] .…”
Section: Discussionmentioning
confidence: 99%