2017
DOI: 10.1590/s0102-865020170040000007
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Abstract: IVDevelopment of a new model of actinic enteritis in rats using a cobalt-60 open source and a protection device as a collimator 1 7-Technical SkillActa Cir Bras. 2017;32(3):319-324 AbstractPurpose: To describe a new model of actinic enteritis that does not use radiotherapy machines. Methods: Sixteen Wistar rats were divided into four groups, consisting of four animals each: control (group A), two weeks after irradiation (group B), five weeks after irradiation (group C) and eight weeks after irradiation (group … Show more

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Cited by 2 publications
(2 citation statements)
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“…To test new modalities of treatment, animal models are widely used as they simulate human pathologies with a very reliable similarity 17 . Recently, a new technique for pelvic radiation in rats was developed 14 , and this was one of the first experiment in which this novel approach was used. It proved efficacious as the expected histological parameters were determined in the rats as they would have been in humans with actinic proctitis.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…To test new modalities of treatment, animal models are widely used as they simulate human pathologies with a very reliable similarity 17 . Recently, a new technique for pelvic radiation in rats was developed 14 , and this was one of the first experiment in which this novel approach was used. It proved efficacious as the expected histological parameters were determined in the rats as they would have been in humans with actinic proctitis.…”
Section: Discussionmentioning
confidence: 99%
“…Most of the research available is based on radiation given by teletherapy machines. Our research group previously described a new method for inducing experimental actinic proctitis using a natural source of radiation in a nuclear technology research center (Centro de Desenvolvimento da Tecnologia Nuclear), which has proven effective and feasible 14 .…”
Section: Introductionmentioning
confidence: 99%