Assessment of Maximum Bite Force in Oral Submucous Fibrosis Patients: A Preliminary Study

Patil, Santosh; Maragathavalli, G; Ramesh, DNSV; Vargheese, Sheeja; Al-Zoubi, Ibrahim A; Alam, Mohammad Khursheed

doi:10.1590/pboci.2020.009

Cited by 14 publications

(15 citation statements)

References 13 publications

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“…The study on the combination of both antioxidant and cytotoxic effects of Selenium nanoparticles as a subject is the uniqueness of our study. Our recent research portfolio slides numerous articles in reputed journals [22][23][24][25][26][27][28][29][30]. Based on this experience we planned to pursue the cytotoxicity and antioxidant property of Selenium nanoparticles.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antioxidant and Cytotoxic Effect of Selenium Nanoparticles Synthesised Using Capparis decidua

Lakshme

Preetha

Jeevitha

et al. 2020

JPRI

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Background: Among the nanoparticles, selenium nanoparticles (SeNP) are one of the most extensively studied as Selenium has zero oxidation state, non toxic and biologically inert material. This is the reason why Selenium is considered as a major nanoparticulate. In this study SeNPs were extracted from the fruit of Capparis decidua which is a xerophytic small herb. Aim: The aim of the present study is to evaluate the cytotoxic effect and antioxidant capacity of selenium nanoparticles. Materials and Methods: In this study SeNPs were extracted from the fruit of Capparis decidua which is a xerophytic small herb. The cytotoxic effect of SeNPs was evaluated using Brine Shrimp assay and the antioxidant activity was determined using DPPH assay considering ascorbic acid as the standard. Results: From the study of this assay the shrimps introduced into the well were almost alive in different concentrations and this indicates that there is no cytotoxicity in selenium nanoparticles. The percentage inhibition of Selenium nanoparticles in 10 µl was 15.4 0.1, 20 µl was 38.36 0.15, 30 µl was 45.3 0.1, 40 µl was 59.6 0.15 and 50 µl was 65.6 0.1. It can be inferred that percentage inhibition increases with increase in concentration but it was less when compared to the percentage inhibition of the standard. Conclusion: The selenium nanoparticles extracted from Capparis decidua do not have any cytotoxic effect on shrimps. The SeNPs possessed significant antioxidant activity in increasing concentrations compared to the standard used. Thus SeNPs are biologically useful and can be used as eco-friendly, cost effective and efficient biomedical agents and therapeutics.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Antioxidant and Cytotoxic Effect of Selenium Nanoparticles Synthesised Using Capparis decidua

Lakshme

Preetha

Jeevitha

et al. 2020

JPRI

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“…Our recent research portfolio slides numerous articles in reputed journals [13][14][15][16][17]. Based on this experience we planned to pursue the evaluation of calcium and alkaline phosphatase in the salivary samples of premenopausal and postmenopausal women.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Calcium and Alkaline Phosphatase in the Salivary Samples of Premenopausal and Postmenopausal Women

Baskar

Dharman

2020

JPRI

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The quality of life for women after menopause is one of the key health issues today. Rapid bone loss occurs in post-menopausal women due to hormonal factors that lead to an increased risk of fractures. The aim of the study is to evaluate the calcium and Alkaline phosphate levels (ALP) in the salivary samples of premenopausal and postmenopausal women. The study was conducted with a sample size of 30, with 15 samples from premenopausal women belonging to the age group of 40-46 years and 15 samples from postmenopausal women aged more than 50 years. Calcium and alkaline phosphatase levels were estimated using the commercial kits available which were Spinreact and Accucare alkaline phosphatase respectively. The statistical analysis was done using independent t-test. Saliva was stimulated and biochemical analysis of these salivary samples was done to evaluate the calcium and alkaline phosphatase. Mean salivary calcium in premenopausal women was found to be 7.37±1.141 mg/dl and in postmenopausal women it was found to be 5.19±1.141mg/dl,P=0.000(p<0.05). Mean salivary ALP levels in premenopausal women was found to be 10.81±3.295 mg/dl and in postmenopausal women was found to be 33.58±3.295 mg/dl, P=0.001(p <0.05), hence statistically significant. Within the limitations of the study, it was found that calcium were found to be significantly more in premenopausal women when compared to postmenopausal women, while alkaline phosphatase levels were increased in postmenopausal women when compared to premenopausal women. Hence, salivary calcium and ALP levels can be used as biomarkers for diagnosis of bone diseases as it is a non-invasive technique.

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“…Analysis of saliva will offer an economical approach for screening of enormous populations [9]. Our recent research portfolio slides numerous articles in reputed journals [15][16][17][18][19]. Based on this experience, we planned to investigate the correlation between blood glucose levels with salivary glucose levels in diabetes patients.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Salivary and Blood Glucose Level among Patients with Diabetes Mellitus – A Comparative Study

Sagana

Dharman

2020

JPRI

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Diabetes mellitus (DM) is a clinical syndrome characterized by hyperglycemia because of the absolute or relative deficiency of insulin. It requires frequent monitoring of glucose levels in the body which requires multiple pricking at regular intervals. It could be physically and psychologically traumatic to the patient. This necessitates an alternative to measure the glucose level. This study aims to correlate the salivary glucose level with the blood glucose level in diabetes patients. The cross-sectional study was conducted in 60 patients. Patients were categorized into two groups as Group A- 30 patients with diabetes and Group B- 30 healthy subjects. The blood and saliva samples were collected from the patients and the glucose levels were recorded. All these data were entered in Microsoft Excel and analyzed statistically using SPSS software. The mean (±SD) value of the random blood and salivary glucose level in diabetic patients were found to be 251.4±82.66 and 2.85±0.85 respectively and the mean blood and salivary glucose level in healthy subjects were found to be 101.12±10.14 and 0.875±0.13 respectively. There was a significant correlation between the salivary glucose levels and blood glucose levels among diabetes (p-0.00) and healthy individuals (p-0.00). From the data, the diagnostic accuracy was found to be 100%. Thus, Saliva could be used as an alternative to blood for monitoring the glucose status in diabetes patients.

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Assessment of Maximum Bite Force in Oral Submucous Fibrosis Patients: A Preliminary Study

Cited by 14 publications

References 13 publications

Evaluation of Antioxidant and Cytotoxic Effect of Selenium Nanoparticles Synthesised Using Capparis decidua

Evaluation of Antioxidant and Cytotoxic Effect of Selenium Nanoparticles Synthesised Using Capparis decidua

Evaluation of Calcium and Alkaline Phosphatase in the Salivary Samples of Premenopausal and Postmenopausal Women

Estimation of Salivary and Blood Glucose Level among Patients with Diabetes Mellitus – A Comparative Study

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