2018
DOI: 10.1590/abd1806-4841.20187171
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Abstract: Amicrobial pustulosis of the folds is a chronic relapsing neutrophilic dermatosis characterized by sterile pustules compromising skin folds, scalp, face and periorificial regions. It predominantly affects women. Demodicosis is an inflammatory disease associated with cutaneous overpopulation of the mite Demodex spp., the pathogenesis of which is not completely established, but is frequently related to local immunodeficiency. A case of a young woman with amicrobial pustulosis of the folds, and isolated worsening… Show more

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Cited by 7 publications
(4 citation statements)
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“…Furthermore, German Shepherds are predisposed to primary immunodeficiency (16) and it has been postulated that high microfilaremia might be associated with a state of immunosuppression (17). The chronic yeast infection (usually secondary to an immune disorder in dogs) as well as the appearance of generalized demodicosis are possible indicators of immunodeficiency in this patient (18,19).…”
Section: Discussionmentioning
confidence: 86%
“…Furthermore, German Shepherds are predisposed to primary immunodeficiency (16) and it has been postulated that high microfilaremia might be associated with a state of immunosuppression (17). The chronic yeast infection (usually secondary to an immune disorder in dogs) as well as the appearance of generalized demodicosis are possible indicators of immunodeficiency in this patient (18,19).…”
Section: Discussionmentioning
confidence: 86%
“…In addition, inflammation and the development of further complications are often associated with the transmission of bacterial infections, e.g., B. oleronius , S. aureus , or fungal infections carried along with the Demodex spp. [ 127 ]. In demodicosis and rosacea, the importance of the immune response is emphasized.…”
Section: Discussionmentioning
confidence: 99%
“…15 The literature describes cases of patients who consulted dermatologists about skin lesions and used various treatments with different groups of drugs, but none of them brought the expected results. 16 This situation is difficult both for the doctor who is trying to prescribe more effective drugs and for the patient who expects visible improvement.…”
Section: Discussionmentioning
confidence: 99%