2017
DOI: 10.1590/abd1806-4841.20175972
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Abstract: We report the ultrastructural findings in a case of a 72-year-old black woman with confluent yellowish papules in the cervical region. She had no comorbidities. Ophthalmological examination, electrocardiogram, and echocardiogram were normal. Hematoxylin-eosin staining of the affected skin showed strong alterations in the mid-dermis with irregular clumps of eosinophilic material and loss of the normal parallel arrangement of collagen bundles. Orcein staining revealed that the elastic fibers lost their normal li… Show more

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Cited by 4 publications
(2 citation statements)
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“…These findings of deposits resembling small stones or pebbles have already been described in other dermal conditions, demonstrating the superiority of TEM in the analysis of elastic fibers, with a better demonstration of the internal changes in fibers in tissue sections. 8 , 9 These findings are in agreement with a previous publication, which showed that initial lesions have deposits in more affected areas, large amorphous masses, and that the elastotic material is comprised of elastic fibers. 10 The deposition of amorphous material associated with elastic fiber degeneration has been reported, as well as preserved collagen fibers and bundle disorganization.…”
Section: Discussionsupporting
confidence: 91%
“…These findings of deposits resembling small stones or pebbles have already been described in other dermal conditions, demonstrating the superiority of TEM in the analysis of elastic fibers, with a better demonstration of the internal changes in fibers in tissue sections. 8 , 9 These findings are in agreement with a previous publication, which showed that initial lesions have deposits in more affected areas, large amorphous masses, and that the elastotic material is comprised of elastic fibers. 10 The deposition of amorphous material associated with elastic fiber degeneration has been reported, as well as preserved collagen fibers and bundle disorganization.…”
Section: Discussionsupporting
confidence: 91%
“…These findings are different from other diseases with malformations of elastic fibres, such as pseudoxanthoma elasticum, with most fibres exhibiting rounded aggregates, 8 but may be…”
contrasting
confidence: 84%