Hemosiderotic dermatofibroma

Abstract

We report a rare clinical case of hemosiderotic dermatofibroma in a 36-year-old female patient. The main dermatoscopic finding was represented by homogeneous blue-gray pigmentation. The aim of this report is to demonstrate the rarity of the lesion and the dermatoscopic importance it assumes by sharing a blue-gray homogeneous pattern with other benign and malignant lesions.

Hemosiderotic dermatofibroma mimicking melanoma: A case report and review of the literature

“…Majority of these cases raise concern for melanoma following initial dermatoscopic examination and excision was performed for a definite diagnosis. 11,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] The area rich in poorly formed vessel-like structures can make the lesion look like a vascular tumor such as Kaposi's sarcoma both microscopically and clinically. 28 Given the patient having no clinical history of immunosuppressive diseases/conditions, the chance of Kaposi's sarcoma is likely to be very low.…”

Erythematous to bluish nodule on the face in a young male

“…[ 5 ] It is a rare though distinct variant, comprising 2–5.7% of all dermatofibromas. [ 1 6 ] It has been described at various anatomical sites like the abdomen, breast, and leg as a blue-gray, dark brown or black nodule or plaque, which may sometimes simulate melanoma. [ 5 6 7 8 ]…”

Hemosiderotic Dermatofibroma: A Rare and Atypical Variant Capable of Clinically Resembling Melanoma

“…The physical presentation of HDF and melanoma is similar and can appear as a variably pigmented papule, plaque, or hardened nodule [12]. In cases where the HDF is not removed, it is hypothesized that the red blood cells would extravasate from small vessels, eventually producing hemosiderin, which would be taken up by the tumor cells [13]. Over time, the extravasation would create intravascular spaces, thereby increasing internal tumor pressure and creating endothelial damage [13].…”

“…In cases where the HDF is not removed, it is hypothesized that the red blood cells would extravasate from small vessels, eventually producing hemosiderin, which would be taken up by the tumor cells [13]. Over time, the extravasation would create intravascular spaces, thereby increasing internal tumor pressure and creating endothelial damage [13]. At this stage, the HDF could be considered an early ADF [14].…”