2014
DOI: 10.1590/abd1806-4841.20142857
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Abstract: Leprosy is clinically characterized by involvement of peripheral nerves and skin. The immunological profile of the individual defines the diversity of clinical manifestations, from skin disorders to systemic manifestations, especially the articulation ones, common in multibacillary forms, which may mimic collagen diseases and often posing diagnostic difficulties in endemic areas. This is a case report of asymmetric polyarthritis of small and large articulations associated with skin lesions which had been treat… Show more

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Cited by 11 publications
(6 citation statements)
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“… 4 , 8 Proposed mechanisms include reactional states, direct infiltration of the synovium, and peripheral sensory neuropathy leading to joint destruction. 4 , 9 , 12 There is no official classification of arthritis in leprosy. Nevertheless, arthritis in leprosy can be categorized into the following groups: (i) Charcot’s joints, (ii) septic arthritis, (iii) acute polyarthritis of lepra reaction, and (iv) chronic arthritis.…”
Section: Discussionmentioning
confidence: 99%
“… 4 , 8 Proposed mechanisms include reactional states, direct infiltration of the synovium, and peripheral sensory neuropathy leading to joint destruction. 4 , 9 , 12 There is no official classification of arthritis in leprosy. Nevertheless, arthritis in leprosy can be categorized into the following groups: (i) Charcot’s joints, (ii) septic arthritis, (iii) acute polyarthritis of lepra reaction, and (iv) chronic arthritis.…”
Section: Discussionmentioning
confidence: 99%
“…[ 5 ] The insidious onset of chronic symmetrical poly-arthritis may be easily misdiagnosed as RA, independent or arthritis-related neuropathy or tenosynovitis. The prevalence of Hansen disease-related arthritis is described in up to 75% of these patients, which can be accompanied by or precede skin lesions and may be the only manifestation, [ 5 7 ] and it is the third commonest after dermatological and neurological manifestations. [ 8 ] The bone joint damage caused by Hansen disease is divided into three categories: direct bone damage, mainly in leprosy osteitis and expansive bone destruction; secondary bone joint damage due to neurovascular disease, mainly in bone resorption and Charcot's joint; osteoporosis.…”
Section: Discussionmentioning
confidence: 99%
“…The clinical features with a classic skin lesion with acute polyarthritis led to the diagnosis of leprosy. Clinical presentation mimics RA or systemic lupus erythema (SLE), leprosy lesions classical affect the peripheral nerves, particularly the posterior tibial, ulnar, median, and peroneus common nerve, such as numb skin lesions and thickening nerves, and nerve pain enhances leprosy [8], [9]. Sometimes, it is difficult to differentiate symmetrical polyarthritis due to leprosy from RA as in our patient.…”
Section: Discussionmentioning
confidence: 74%