2014
DOI: 10.1590/abd1806-4841.20142146
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Abstract: Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new criteria for the diagnosis of the disease, according to the Systemic Lupus International Collaborating Clinics. The cutaneous manifestations of lupus are pleomorphic. Depending on their clinical characteristics, they can be classified into Acute Cutaneous Lupus Er… Show more

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Cited by 16 publications
(14 citation statements)
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“…Further systemic treatment options for CLE include methotrexate, rituximab, retinoids, dapsone, thalidomide, mycophenolate mofetil, and azathioprine. In addition to the pharmacological treatment options for ACLE, it is crucial to educate the patient on the importance of sun protection and tobacco cessation [1][2][3]6,7].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Further systemic treatment options for CLE include methotrexate, rituximab, retinoids, dapsone, thalidomide, mycophenolate mofetil, and azathioprine. In addition to the pharmacological treatment options for ACLE, it is crucial to educate the patient on the importance of sun protection and tobacco cessation [1][2][3]6,7].…”
Section: Discussionmentioning
confidence: 99%
“…Many patients with systemic lupus erythematosus (SLE) suffer from a variety of dermatological conditions. In fact, 80% of patients have skin lesions at some point in their disease, and up to one-fourth of patients have cutaneous findings at the point of diagnosis [1]. The cutaneous involvement seen in SLE is typically separated into "specific" and "non-specific" skin manifestations.…”
Section: Introductionmentioning
confidence: 99%
“…The treatment of LE, including oral mucosal manifestation, is a complex and multidisciplinary process, which is based on preventive measures, inflammatory process modulation and control, organ injury prevention, relief of the symptoms [27]. Prevention could be done by managing and monitoring patient´s lifestyle habits.…”
Section: Treatmentmentioning
confidence: 99%
“…Its clinical manifestations are ample, and may involve any organism component, simultaneously or in stages, during any illness period [2] [7].…”
Section: Introductionmentioning
confidence: 99%
“…Cutaneous lesions constitute 4 of the 17 new criteria established by the International Systemic Lupus Collaborative Clinics (ISDCC) in 2012, for SLE diagnosis: acute cutaneous lupus, chronic cutaneous lupus, oral ulcers and non-healingalopecia [7]. The patient's history, clinical and laboratory tests, serology and histopathological examination should be the basis for CLE diagnosis [11] [12] [13].…”
Section: Introductionmentioning
confidence: 99%